Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human african trypanosomiasis

Lauren Sullivan, Jennifer Fleming, Lalitha Sastry, Angela Mehlert, Steven J Wall, Michael A J Ferguson (Lead / Corresponding author)

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    Abstract

    The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense. Our principle aim was to develop a prototype lateral flow test that might be an improvement on CATT.

    Original languageEnglish
    Pages (from-to)e2976
    JournalPLoS Neglected Tropical Diseases
    Volume8
    Issue number7
    DOIs
    Publication statusPublished - 17 Jul 2014

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