Image-guided breast biopsy and localisation: recommendations for information to women and referring physicians by the European Society of Breast Imaging

European Society of Breast Imaging (EUSOBI), Europa Donna-The European Breast Cancer Coalition, Ulrich Bick, Rubina M. Trimboli, Alexandra Athanasiou, Corinne Balleyguier, Pascal A. T. Baltzer, Maria Bernathova, Krisztina Borbély, Boris Brkljacic, Luca A. Carbonaro, Paola Clauser, Enrico Cassano, Catherine Colin, Gul Esen, Andrew Evans, Eva M. Fallenberg, Michael H. Fuchsjaeger, Fiona J. Gilbert, Thomas H. HelbichSylvia H. Heywang-Köbrunner, Michel Herranz, Karen Kinkel, Fleur Kilburn-Toppin, Christiane K. Kuhl, Mihai Lesaru, Marc B. I. Lobbes, Ritse M. Mann, Laura Martincich, Pietro Panizza, Federica Pediconi, Ruud M. Pijnappel, Katja Pinker, Simone Schiaffino, Tamar Sella, Isabelle Thomassin-Naggara, Anne Tardivon, Chantal Van Ongeval, Matthew G. Wallis, Sophia Zackrisson, Gabor Forrai, Julia Camps Herrero, Francesco Sardanelli (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

89 Citations (Scopus)
133 Downloads (Pure)


We summarise here the information to be provided to women and referring physicians about percutaneous breast biopsy and lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with a percutaneous biopsy is preferred to surgical biopsy, we illustrate the criteria used by radiologists for choosing the most appropriate combination of device type for sampling and imaging technique for guidance. Then, we describe the commonly used devices, from fine-needle sampling to tissue biopsy with larger needles, namely core needle biopsy and vacuum-assisted biopsy, and how mammography, digital breast tomosynthesis, ultrasound, or magnetic resonance imaging work for targeting the lesion for sampling or localisation. The differences among the techniques available for localisation (carbon marking, metallic wire, radiotracer injection, radioactive seed, and magnetic seed localisation) are illustrated. Type and rate of possible complications are described and the issue of concomitant antiplatelet or anticoagulant therapy is also addressed. The importance of pathological-radiological correlation is highlighted: when evaluating the results of any needle sampling, the radiologist must check the concordance between the cytology/pathology report of the sample and the radiological appearance of the biopsied lesion. We recommend that special attention is paid to a proper and tactful approach when communicating to the woman the need for tissue sampling as well as the possibility of cancer diagnosis, repeat tissue sampling, and or even surgery when tissue sampling shows a lesion with uncertain malignant potential (also referred to as "high-risk" or B3 lesions). Finally, seven frequently asked questions are answered.

Original languageEnglish
Article number12
Pages (from-to)1-18
Number of pages18
JournalInsights into Imaging
Issue number1
Early online date5 Feb 2020
Publication statusPublished - Dec 2020


  • Breast
  • Breast lesion localisation
  • Core needle biopsy
  • Fine-needle sampling
  • Vacuum-assisted biopsy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Image-guided breast biopsy and localisation: recommendations for information to women and referring physicians by the European Society of Breast Imaging'. Together they form a unique fingerprint.

Cite this