Immunocytochemical localization of ferritin in the kidney and renal tumours

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    Abstract

    The distribution of ferritin in the kidney and renal tumors was studied using a polyclonal anti-ferritin antiserum and immunocytochemical techniques. Ten fetal kidneys, 5 adult kidneys and 56 renal tumours were studied. Ferritin first appears in the maturing fetal nephron where it is confined to the proximal tubule. In the adult kidney ferritin is also restricted to the proximal tubule. Ferritin was not seen in 18 nephroblastomas nor in 4 renal sarcomas, but 14 of 26 renal cell carcinomas and 5 of 8 renal oncocytomas contained ferritin. The relationship between the expression of ferritin and tumour differentiation is discussed.
    Original languageEnglish
    Pages (from-to)407-411
    Number of pages5
    JournalEuropean Urology
    Volume13
    Issue number6
    Publication statusPublished - 1987

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    Ferritins
    Kidney
    Neoplasms
    Wilms Tumor
    Nephrons
    Renal Cell Carcinoma
    Sarcoma
    Immune Sera

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    title = "Immunocytochemical localization of ferritin in the kidney and renal tumours",
    abstract = "The distribution of ferritin in the kidney and renal tumors was studied using a polyclonal anti-ferritin antiserum and immunocytochemical techniques. Ten fetal kidneys, 5 adult kidneys and 56 renal tumours were studied. Ferritin first appears in the maturing fetal nephron where it is confined to the proximal tubule. In the adult kidney ferritin is also restricted to the proximal tubule. Ferritin was not seen in 18 nephroblastomas nor in 4 renal sarcomas, but 14 of 26 renal cell carcinomas and 5 of 8 renal oncocytomas contained ferritin. The relationship between the expression of ferritin and tumour differentiation is discussed.",
    author = "S. Fleming",
    year = "1987",
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    Immunocytochemical localization of ferritin in the kidney and renal tumours. / Fleming, S.

    In: European Urology, Vol. 13, No. 6, 1987, p. 407-411.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Immunocytochemical localization of ferritin in the kidney and renal tumours

    AU - Fleming, S.

    PY - 1987

    Y1 - 1987

    N2 - The distribution of ferritin in the kidney and renal tumors was studied using a polyclonal anti-ferritin antiserum and immunocytochemical techniques. Ten fetal kidneys, 5 adult kidneys and 56 renal tumours were studied. Ferritin first appears in the maturing fetal nephron where it is confined to the proximal tubule. In the adult kidney ferritin is also restricted to the proximal tubule. Ferritin was not seen in 18 nephroblastomas nor in 4 renal sarcomas, but 14 of 26 renal cell carcinomas and 5 of 8 renal oncocytomas contained ferritin. The relationship between the expression of ferritin and tumour differentiation is discussed.

    AB - The distribution of ferritin in the kidney and renal tumors was studied using a polyclonal anti-ferritin antiserum and immunocytochemical techniques. Ten fetal kidneys, 5 adult kidneys and 56 renal tumours were studied. Ferritin first appears in the maturing fetal nephron where it is confined to the proximal tubule. In the adult kidney ferritin is also restricted to the proximal tubule. Ferritin was not seen in 18 nephroblastomas nor in 4 renal sarcomas, but 14 of 26 renal cell carcinomas and 5 of 8 renal oncocytomas contained ferritin. The relationship between the expression of ferritin and tumour differentiation is discussed.

    M3 - Article

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    VL - 13

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    EP - 411

    JO - European Urology

    JF - European Urology

    SN - 0302-2838

    IS - 6

    ER -