Impact of COVID-19 on diagnosis and management of paediatric inflammatory bowel disease during lockdown: a UK nationwide study

James John Ashton, Jochen Kammermeier, Christine Spray, Richard K. Russell, Richard Hansen, Lucy J. Howarth, Franco Torrente, Protima Deb, Elizabeth Renji, Rafeeq Muhammed, Thankam Paul, Fevronia Kiparissi, Jenny Epstein, Maureen Lawson, Ben Hope, Veena Zamvar, Priya Narula, Ahmed Kadir, David Devadason, Hemant BhavsarRobert Mark Beattie

    Research output: Contribution to journalArticlepeer-review

    28 Citations (Scopus)

    Abstract

    Background: COVID-19 has impacted on healthcare provision. Anecdotally, investigations for children with inflammatory bowel disease (IBD) have been restricted, resulting in diagnosis with no histological confirmation and potential secondary morbidity. In this study, we detail practice across the UK to assess impact on services and document the impact of the pandemic. 

    Methods: For the month of April 2020, 20 tertiary paediatric IBD centres were invited to contribute data detailing: (1) diagnosis/management of suspected new patients with IBD; (2) facilities available; (3) ongoing management of IBD; and (4) direct impact of COVID-19 on patients with IBD. 

    Results: All centres contributed. Two centres retained routine endoscopy, with three unable to perform even urgent IBD endoscopy. 122 patients were diagnosed with IBD, and 53.3% (n=65) were presumed diagnoses and had not undergone endoscopy with histological confirmation. The most common induction was exclusive enteral nutrition (44.6%). No patients with a presumed rather than confirmed diagnosis were started on anti-tumour necrosis factor (TNF) therapy. Most IBD follow-up appointments were able to occur using phone/webcam or face to face. No biologics/immunomodulators were stopped. All centres were able to continue IBD surgery if required, with 14 procedures occurring across seven centres. 

    Conclusions: Diagnostic IBD practice has been hugely impacted by COVID-19, with >50% of new diagnoses not having endoscopy. To date, therapy and review of known paediatric patients with IBD has continued. Planning and resourcing for recovery is crucial to minimise continued secondary morbidity.

    Original languageEnglish
    Pages (from-to)1186-1191
    Number of pages6
    JournalArchives of Disease in Childhood
    Volume105
    Issue number12
    Early online date30 Jul 2020
    DOIs
    Publication statusPublished - 20 Nov 2020

    Keywords

    • Gastroenterology
    • Health services research

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health

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