Improving recruitment of older people to research through good practice

Marion E. T. McMurdo, Helen Roberts, Stuart Parker, Nikki Wyatt, Helen May, Claire Goodman, Stephen Jackson, John Gladman, Sinead O'Mahony, Khalid Ali, Edward Dickinson, Paul Edison, Chris Dyer, Comprehensive Clinical Res Network

    Research output: Contribution to journalReview article

    123 Citations (Scopus)

    Abstract

    There is widespread evidence both of the exclusion of older people from clinical research, and of under-recruitment to clinical trials. This review and opinion piece provides practical advice to assist researchers both to adopt realistic, achievable recruitment rates and to increase the number of older people taking part in research. It analyses 14 consecutive recently published trials, providing the number needed to be screened to recruit one older participant (around 3:1), numbers excluded (up to 49%), drop out rates (5-37%) and whether the planned power was achieved. The value of planning and logistics are outlined, and approaches to optimising recruitment in hospital, primary care and care home settings are discussed, together with the challenges of involving older adults with mental incapacity and those from minority groups in research. The increasingly important task of engaging older members of the public and older patients in research is also discussed. Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population.

    Original languageEnglish
    Pages (from-to)659-665
    Number of pages7
    JournalAge and Ageing
    Volume40
    Issue number6
    DOIs
    Publication statusPublished - Nov 2011

    Keywords

    • recruitment
    • clinical trials
    • efficiency
    • older
    • elderly
    • RANDOMIZED CONTROLLED-TRIAL
    • CLINICAL-TRIALS
    • COMMUNITY
    • WOMEN
    • PREVENTION
    • FALLS
    • HOME
    • INTERVENTION
    • PHYSICIANS
    • MOBILITY

    Cite this

    McMurdo, M. E. T., Roberts, H., Parker, S., Wyatt, N., May, H., Goodman, C., ... Comprehensive Clinical Res Network (2011). Improving recruitment of older people to research through good practice. Age and Ageing, 40(6), 659-665. https://doi.org/10.1093/ageing/afr115
    McMurdo, Marion E. T. ; Roberts, Helen ; Parker, Stuart ; Wyatt, Nikki ; May, Helen ; Goodman, Claire ; Jackson, Stephen ; Gladman, John ; O'Mahony, Sinead ; Ali, Khalid ; Dickinson, Edward ; Edison, Paul ; Dyer, Chris ; Comprehensive Clinical Res Network. / Improving recruitment of older people to research through good practice. In: Age and Ageing. 2011 ; Vol. 40, No. 6. pp. 659-665.
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    abstract = "There is widespread evidence both of the exclusion of older people from clinical research, and of under-recruitment to clinical trials. This review and opinion piece provides practical advice to assist researchers both to adopt realistic, achievable recruitment rates and to increase the number of older people taking part in research. It analyses 14 consecutive recently published trials, providing the number needed to be screened to recruit one older participant (around 3:1), numbers excluded (up to 49{\%}), drop out rates (5-37{\%}) and whether the planned power was achieved. The value of planning and logistics are outlined, and approaches to optimising recruitment in hospital, primary care and care home settings are discussed, together with the challenges of involving older adults with mental incapacity and those from minority groups in research. The increasingly important task of engaging older members of the public and older patients in research is also discussed. Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population.",
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    author = "McMurdo, {Marion E. T.} and Helen Roberts and Stuart Parker and Nikki Wyatt and Helen May and Claire Goodman and Stephen Jackson and John Gladman and Sinead O'Mahony and Khalid Ali and Edward Dickinson and Paul Edison and Chris Dyer and {Comprehensive Clinical Res Network}",
    year = "2011",
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    McMurdo, MET, Roberts, H, Parker, S, Wyatt, N, May, H, Goodman, C, Jackson, S, Gladman, J, O'Mahony, S, Ali, K, Dickinson, E, Edison, P, Dyer, C & Comprehensive Clinical Res Network 2011, 'Improving recruitment of older people to research through good practice', Age and Ageing, vol. 40, no. 6, pp. 659-665. https://doi.org/10.1093/ageing/afr115

    Improving recruitment of older people to research through good practice. / McMurdo, Marion E. T.; Roberts, Helen; Parker, Stuart; Wyatt, Nikki; May, Helen; Goodman, Claire; Jackson, Stephen; Gladman, John; O'Mahony, Sinead; Ali, Khalid; Dickinson, Edward; Edison, Paul; Dyer, Chris; Comprehensive Clinical Res Network.

    In: Age and Ageing, Vol. 40, No. 6, 11.2011, p. 659-665.

    Research output: Contribution to journalReview article

    TY - JOUR

    T1 - Improving recruitment of older people to research through good practice

    AU - McMurdo, Marion E. T.

    AU - Roberts, Helen

    AU - Parker, Stuart

    AU - Wyatt, Nikki

    AU - May, Helen

    AU - Goodman, Claire

    AU - Jackson, Stephen

    AU - Gladman, John

    AU - O'Mahony, Sinead

    AU - Ali, Khalid

    AU - Dickinson, Edward

    AU - Edison, Paul

    AU - Dyer, Chris

    AU - Comprehensive Clinical Res Network

    PY - 2011/11

    Y1 - 2011/11

    N2 - There is widespread evidence both of the exclusion of older people from clinical research, and of under-recruitment to clinical trials. This review and opinion piece provides practical advice to assist researchers both to adopt realistic, achievable recruitment rates and to increase the number of older people taking part in research. It analyses 14 consecutive recently published trials, providing the number needed to be screened to recruit one older participant (around 3:1), numbers excluded (up to 49%), drop out rates (5-37%) and whether the planned power was achieved. The value of planning and logistics are outlined, and approaches to optimising recruitment in hospital, primary care and care home settings are discussed, together with the challenges of involving older adults with mental incapacity and those from minority groups in research. The increasingly important task of engaging older members of the public and older patients in research is also discussed. Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population.

    AB - There is widespread evidence both of the exclusion of older people from clinical research, and of under-recruitment to clinical trials. This review and opinion piece provides practical advice to assist researchers both to adopt realistic, achievable recruitment rates and to increase the number of older people taking part in research. It analyses 14 consecutive recently published trials, providing the number needed to be screened to recruit one older participant (around 3:1), numbers excluded (up to 49%), drop out rates (5-37%) and whether the planned power was achieved. The value of planning and logistics are outlined, and approaches to optimising recruitment in hospital, primary care and care home settings are discussed, together with the challenges of involving older adults with mental incapacity and those from minority groups in research. The increasingly important task of engaging older members of the public and older patients in research is also discussed. Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population.

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    KW - clinical trials

    KW - efficiency

    KW - older

    KW - elderly

    KW - RANDOMIZED CONTROLLED-TRIAL

    KW - CLINICAL-TRIALS

    KW - COMMUNITY

    KW - WOMEN

    KW - PREVENTION

    KW - FALLS

    KW - HOME

    KW - INTERVENTION

    KW - PHYSICIANS

    KW - MOBILITY

    U2 - 10.1093/ageing/afr115

    DO - 10.1093/ageing/afr115

    M3 - Review article

    C2 - 21911335

    VL - 40

    SP - 659

    EP - 665

    JO - Age and Ageing

    JF - Age and Ageing

    SN - 0002-0729

    IS - 6

    ER -