In-phase bilateral arm movements facilitate smoother movement in acute stroke

a kinematic and fMRI study

P. L. Choo, J McLean, Helen L. Gallagher, Jacqui Morris, Frederike Van Wijck

Research output: Contribution to journalMeeting abstract

Abstract

Introduction: Bilateral upper limb training (BT) is a potential stroke rehabilitation intervention.
Comparing unilateral and bilateral BT modes using kinematic assessments and neuroimaging allows
understanding of the cortical and behavioural mechanisms of action underlying BT. This study aimed to
compare the effects of unilateral, bilateral in-phase and anti-phase modes of a functional task on
paretic arm kinematics alongside functional magnetic resonance imaging (fMRI) in acute stroke.
Methods: 13 acute stroke individuals underwent 3D motion capture of the unilateral, bilateral inphase and anti-phase modes of a functional grasp task. Intralimb kinematics was assessed through
movement time, peak velocity, movement smoothness and movement directness. fMRI scanning was
undertaken using continuous wrist flexion-extension.
Results: Bilateral in-phase grasp task was performed with significantly smoother paretic arm movement compared to unilateral task mode (Z ¼ 2.510, p ¼ 0.012). Bilateral in-phase grasp task was
performed with significantly smoother paretic arm movement (Z ¼ 2.971, p ¼ 0.003) and more
direct movement (Z ¼ 2.761, p ¼ 0.006) compared to bilateral anti-phase task mode. Bilateral inphase wrist flexion-extension involved greater neural activity in numerous brain regions (inferior
frontal gyrus, superior temporal gyrus, middle temporal gyrus and inferior temporal gyrus of the
lesioned hemisphere) compared to bilateral anti-phase wrist flexion-extension in most participants.
Conclusion: Paretic arm movement became smoother during bilateral in-phase grasp task compared
to unilateral and bilateral anti-phase task modes. Therapists might consider using bilateral in-phase
functional UL tasks on stroke survivors with jerky movements. fMRI demonstrated significant differences in activation/deactivation of brain regions between bilateral in-phase and anti-phase wrist
flexion-extension in acute stroke, providing evidence of differential neural networks
Original languageEnglish
Article number150
Pages (from-to)41-42
Number of pages2
JournalInternational Journal of Stroke : Official Journal of the International Stroke Society
Volume13
Issue number3S
DOIs
Publication statusPublished - 2018

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Hand Strength
Biomechanical Phenomena
Arm
Temporal Lobe
Wrist
Stroke
Magnetic Resonance Imaging
Brain
Neuroimaging
Upper Extremity

Cite this

@article{b17e6299f2e14c1f8f5fea147a250bd6,
title = "In-phase bilateral arm movements facilitate smoother movement in acute stroke: a kinematic and fMRI study",
abstract = "Introduction: Bilateral upper limb training (BT) is a potential stroke rehabilitation intervention.Comparing unilateral and bilateral BT modes using kinematic assessments and neuroimaging allowsunderstanding of the cortical and behavioural mechanisms of action underlying BT. This study aimed tocompare the effects of unilateral, bilateral in-phase and anti-phase modes of a functional task onparetic arm kinematics alongside functional magnetic resonance imaging (fMRI) in acute stroke.Methods: 13 acute stroke individuals underwent 3D motion capture of the unilateral, bilateral inphase and anti-phase modes of a functional grasp task. Intralimb kinematics was assessed throughmovement time, peak velocity, movement smoothness and movement directness. fMRI scanning wasundertaken using continuous wrist flexion-extension.Results: Bilateral in-phase grasp task was performed with significantly smoother paretic arm movement compared to unilateral task mode (Z ¼ 2.510, p ¼ 0.012). Bilateral in-phase grasp task wasperformed with significantly smoother paretic arm movement (Z ¼ 2.971, p ¼ 0.003) and moredirect movement (Z ¼ 2.761, p ¼ 0.006) compared to bilateral anti-phase task mode. Bilateral inphase wrist flexion-extension involved greater neural activity in numerous brain regions (inferiorfrontal gyrus, superior temporal gyrus, middle temporal gyrus and inferior temporal gyrus of thelesioned hemisphere) compared to bilateral anti-phase wrist flexion-extension in most participants.Conclusion: Paretic arm movement became smoother during bilateral in-phase grasp task comparedto unilateral and bilateral anti-phase task modes. Therapists might consider using bilateral in-phasefunctional UL tasks on stroke survivors with jerky movements. fMRI demonstrated significant differences in activation/deactivation of brain regions between bilateral in-phase and anti-phase wristflexion-extension in acute stroke, providing evidence of differential neural networks",
author = "Choo, {P. L.} and J McLean and Gallagher, {Helen L.} and Jacqui Morris and {Van Wijck}, Frederike",
year = "2018",
doi = "DOI: 10.1177/1747493018801108",
language = "English",
volume = "13",
pages = "41--42",
journal = "International Journal of Stroke : Official Journal of the International Stroke Society",
issn = "1747-4930",
publisher = "Wiley",
number = "3S",

}

In-phase bilateral arm movements facilitate smoother movement in acute stroke : a kinematic and fMRI study. / Choo, P. L.; McLean, J; Gallagher, Helen L.; Morris, Jacqui; Van Wijck, Frederike.

In: International Journal of Stroke : Official Journal of the International Stroke Society, Vol. 13, No. 3S, 150, 2018, p. 41-42.

Research output: Contribution to journalMeeting abstract

TY - JOUR

T1 - In-phase bilateral arm movements facilitate smoother movement in acute stroke

T2 - a kinematic and fMRI study

AU - Choo, P. L.

AU - McLean, J

AU - Gallagher, Helen L.

AU - Morris, Jacqui

AU - Van Wijck, Frederike

PY - 2018

Y1 - 2018

N2 - Introduction: Bilateral upper limb training (BT) is a potential stroke rehabilitation intervention.Comparing unilateral and bilateral BT modes using kinematic assessments and neuroimaging allowsunderstanding of the cortical and behavioural mechanisms of action underlying BT. This study aimed tocompare the effects of unilateral, bilateral in-phase and anti-phase modes of a functional task onparetic arm kinematics alongside functional magnetic resonance imaging (fMRI) in acute stroke.Methods: 13 acute stroke individuals underwent 3D motion capture of the unilateral, bilateral inphase and anti-phase modes of a functional grasp task. Intralimb kinematics was assessed throughmovement time, peak velocity, movement smoothness and movement directness. fMRI scanning wasundertaken using continuous wrist flexion-extension.Results: Bilateral in-phase grasp task was performed with significantly smoother paretic arm movement compared to unilateral task mode (Z ¼ 2.510, p ¼ 0.012). Bilateral in-phase grasp task wasperformed with significantly smoother paretic arm movement (Z ¼ 2.971, p ¼ 0.003) and moredirect movement (Z ¼ 2.761, p ¼ 0.006) compared to bilateral anti-phase task mode. Bilateral inphase wrist flexion-extension involved greater neural activity in numerous brain regions (inferiorfrontal gyrus, superior temporal gyrus, middle temporal gyrus and inferior temporal gyrus of thelesioned hemisphere) compared to bilateral anti-phase wrist flexion-extension in most participants.Conclusion: Paretic arm movement became smoother during bilateral in-phase grasp task comparedto unilateral and bilateral anti-phase task modes. Therapists might consider using bilateral in-phasefunctional UL tasks on stroke survivors with jerky movements. fMRI demonstrated significant differences in activation/deactivation of brain regions between bilateral in-phase and anti-phase wristflexion-extension in acute stroke, providing evidence of differential neural networks

AB - Introduction: Bilateral upper limb training (BT) is a potential stroke rehabilitation intervention.Comparing unilateral and bilateral BT modes using kinematic assessments and neuroimaging allowsunderstanding of the cortical and behavioural mechanisms of action underlying BT. This study aimed tocompare the effects of unilateral, bilateral in-phase and anti-phase modes of a functional task onparetic arm kinematics alongside functional magnetic resonance imaging (fMRI) in acute stroke.Methods: 13 acute stroke individuals underwent 3D motion capture of the unilateral, bilateral inphase and anti-phase modes of a functional grasp task. Intralimb kinematics was assessed throughmovement time, peak velocity, movement smoothness and movement directness. fMRI scanning wasundertaken using continuous wrist flexion-extension.Results: Bilateral in-phase grasp task was performed with significantly smoother paretic arm movement compared to unilateral task mode (Z ¼ 2.510, p ¼ 0.012). Bilateral in-phase grasp task wasperformed with significantly smoother paretic arm movement (Z ¼ 2.971, p ¼ 0.003) and moredirect movement (Z ¼ 2.761, p ¼ 0.006) compared to bilateral anti-phase task mode. Bilateral inphase wrist flexion-extension involved greater neural activity in numerous brain regions (inferiorfrontal gyrus, superior temporal gyrus, middle temporal gyrus and inferior temporal gyrus of thelesioned hemisphere) compared to bilateral anti-phase wrist flexion-extension in most participants.Conclusion: Paretic arm movement became smoother during bilateral in-phase grasp task comparedto unilateral and bilateral anti-phase task modes. Therapists might consider using bilateral in-phasefunctional UL tasks on stroke survivors with jerky movements. fMRI demonstrated significant differences in activation/deactivation of brain regions between bilateral in-phase and anti-phase wristflexion-extension in acute stroke, providing evidence of differential neural networks

U2 - DOI: 10.1177/1747493018801108

DO - DOI: 10.1177/1747493018801108

M3 - Meeting abstract

VL - 13

SP - 41

EP - 42

JO - International Journal of Stroke : Official Journal of the International Stroke Society

JF - International Journal of Stroke : Official Journal of the International Stroke Society

SN - 1747-4930

IS - 3S

M1 - 150

ER -