In Vivo Microultrasound Visualisation of Nerve Trauma Due to Regional Anaesthesia Needle Insertion and Injection

Anu Chandra, Graeme McLeod, Judy Yan, Yohannes Soenjaya, Brandon Morningstar, Christine Demore

Research output: Contribution to journalConference articlepeer-review

3 Citations (Scopus)
199 Downloads (Pure)


Regional anesthesia is indicated and commonly used for many surgical procedures. However, intraneural needle insertion and injection is frequent, though unintended, resulting in 10% of patients having post-operative peripheral nerve pain, affecting recovery. The incidence of neuropathy has not decreased over the last decade despite the adoption of ultrasound guided regional anesthesia because of the difficulty interpreting the needle tip position relative to nerves with standard clinical ultrasound imaging systems. This study uses microultrasound for visualising the anatomy of the nerve in the pig model and for confirming the placement of the anesthetic needle while delivering injectate near or in a nerve. The in-line fluid pressure is measured during the injection for different clinical flow rates used during the regional anesthesia procedure. The change in shape and the displacement of the nerve due to the injection is evaluated, and fluid pressure associated with intraneural and extraneural injection. The analysis of the different factors contributing to the nerve trauma showed that there was significant change in pressure measurement with different pigs, flow rate and tissue layers where the needle tip was placed.

Original languageEnglish
Article number8579830
Number of pages3
JournalIEEE International Ultrasonics Symposium, IUS
Publication statusPublished - 1 Jan 2018
Event2018 IEEE International Ultrasonics Symposium, IUS 2018 - Kobe, Japan
Duration: 22 Oct 201825 Oct 2018


  • anaesthetic fluid pressure
  • Microultrasound
  • nerve injury
  • peripheral anaesthesia
  • peripheral nerves
  • regional anesthesia

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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