Incidence of type 1 diabetes has doubled in Kuwaiti children 0-14 years over the last 20 years

Azza A. Shaltout (Lead / Corresponding author), Deborah Wake, Thangavel A. Thanaraj, Dina M. Omar, Dalia Al-AbdulRazzaq, Arshad Channanath, Hessa AlKandari, Majedah Abdulrasoul, Sophie Miller, Nicholas Conway, Jaakko Tuomilehto, Lena Davidsson, on behalf of the Steering Group for the Study of Childhood Diabetes in Kuwait

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Abstract

Aims: This study had 2 aims: to report data on the incidence of childhood-onset type 1 diabetes in Kuwaiti children aged 0-14 years during 2011 to 2013 and to compare the recent data with those collected during 1992 to 1997.

Methods: All newly diagnosed patients were registered through the Childhood-Onset Diabetes eRegistry (CODeR) in 2011-2013, based on the DiaMond protocol used in 1992-1997.

Results: A total of 515 Kuwaiti children (247 boys and 268 girls) aged 0-14 years newly diagnosed with type 1 diabetes were registered from 1 January 2011 to 31 December 2013. Data ascertainment were 96.7%. The mean age ± SD at diagnosis was 8.7 ± 3.4 years in boys and 7.9 ± 3.1 years in girls. The crude incidence rate (95% CI) was 40.9 (37.4-44.6) and the age standardized rate 41.7 (95% 38.1-45.4) per 100,000 per year, 39.3 (34.6-44.4) among boys and 44.1 (39.0-49.7) among girls. A statistically significant increasing trend in incidence was observed as the overall crude incidence rose from 17.7 in 1992-1994 to 40.9 per 100,000 per year in 2011-2013. The Poisson regression model depicting the trend in incidence revealed that, the incidence rates adjusted for age and sex in 2011 to 2013 was 2.3 (95% CI 1.9-2.7) times higher than 1992-1997.

Conclusions: The incidence of type 1 diabetes in Kuwaiti children 0-14 years has doubled in the last 2 decades. The reasons for this increase requires further investigation.

Original languageEnglish
Pages (from-to)761-766
Number of pages6
JournalPediatric Diabetes
Volume18
Issue number8
Early online date16 Dec 2016
DOIs
Publication statusPublished - 13 Nov 2017

Keywords

  • childhood diabetes
  • type 1 diabetes
  • epidemiology
  • incidence
  • time trend

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    Shaltout, A. A., Wake, D., Thanaraj, T. A., Omar, D. M., Al-AbdulRazzaq, D., Channanath, A., AlKandari, H., Abdulrasoul, M., Miller, S., Conway, N., Tuomilehto, J., Davidsson, L., & on behalf of the Steering Group for the Study of Childhood Diabetes in Kuwait (2017). Incidence of type 1 diabetes has doubled in Kuwaiti children 0-14 years over the last 20 years. Pediatric Diabetes, 18(8), 761-766. https://doi.org/10.1111/pedi.12480