Incidental giant cystic pheochromocytoma: a case report and review of the literature

Hollie Alice Clements (Lead / Corresponding author), Michael S. J. Wilson, David M. Smith

Research output: Contribution to journalArticlepeer-review


Introduction: Pheochromocytoma is a tumour arising from the adrenal medulla, which secretes catecholamines. Approximately 20% of pheochromocytomas are cystic and more likely to be asymptomatic. They should be surgically resected as all have a malignant potential and pose cardiovascular risk.

Case presentation: We report the case of a 61-year-old female patient admitted electively for laparoscopic adrenalectomy for a large cystic pheochromocytoma detected incidentally. Diagnosis was confirmed preoperatively by elevated 24-h urinary metanephrines. The patient was treated preoperatively with alpha and beta blockade. Surgery was without complication; she had an uneventful postoperative recovery and no evidence of recurrence at one-year follow-up.

Conclusion: This case highlights the necessity of investigating for biochemical function in all adrenal lesions by measuring metanephrines, even when entirely cystic on imaging. Given the surgical and anaesthetic risk in resection of pheochromocytoma, attaining a preoperative diagnosis allows for careful preoperative planning and safe surgery.

Original languageEnglish
Pages (from-to)64-70
Number of pages7
JournalScottish Medical Journal
Issue number2
Early online date13 Jan 2020
Publication statusPublished - 1 May 2020


  • adrenalectomy
  • cystic
  • laparoscopic
  • metanephrines
  • Pheochromocytoma


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