Increased granulocyte aggregation in vitro in diabetes mellitus

T. A. Elhadd; A. Bancroft; M. McLaren; R. W. Newton; J. J. F. Belch

doi:10.1093/qjmed/90.7.461

Increased granulocyte aggregation in vitro in diabetes mellitus

T. A. Elhadd, A. Bancroft, M. McLaren, R. W. Newton, J. J. F. Belch

Research output: Contribution to journal › Article › peer-review

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Abstract

Having previously shown an increase in white blood cell (WBC) aggregation in groups known to have a high incidence of cardiovascular events, we compared 28 patients with diabetes mellitus and no history or clinical evidence of macrovascular disease with 28 age- and sex-matched normal controls. Patients and controls had blood taken in the morning and analysed for WBC aggregation in vitro using a whole blood technique. WBC aggregation was significantly higher in the diabetic group compared with the normal controls (mean ± SD 31.10 ± 10.26% vs. 25.7 ± 9.38%; p<0.04, Student t-test). WBC aggregation predates the appearance of clinical symptoms of macrovascular disease in diabetes.

Original language	English
Pages (from-to)	461-464
Number of pages	4
Journal	QJM : an International Journal of Medicine
Volume	90
Issue number	7
DOIs	https://doi.org/10.1093/qjmed/90.7.461
Publication status	Published - Jul 1997

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AU - Bancroft, A.

AU - McLaren, M.

AU - Newton, R. W.

AU - Belch, J. J. F.

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Increased granulocyte aggregation in vitro in diabetes mellitus

Abstract

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