Induction of germ-tube formation by Candida albicans in amino acid liquid synthetic medium at 25°C

F. Sabie, G. M. Gadd (Lead / Corresponding author)

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    8 Citations (Scopus)

    Abstract

    Candida albicans (3153A) was found to exhibit extensive germ-tube and mycelial development at 25°C when transferred from amino acid synthetic medium at pH 6 to medium of pH 7. Significant germ-tube formation was detectable after approximately 8 h and in all experimental treatments, the peaks of maximal germination occurred at approximately 40-44 h. Such a transition was not only dependent on the initial pH of the medium but also on the glucose concentration and inoculum size. The optimum initial glucose concentration and inoculum size for maximal germ-tube development was 1.25% and 2×106 cells ml-1 respectively and above or below these values the extent of germ-tube formation was greatly reduced.

    Original languageEnglish
    Pages (from-to)77-83
    Number of pages7
    JournalMycopathologia
    Volume101
    Issue number2
    DOIs
    Publication statusPublished - Feb 1988

    Keywords

    • Candida albicans
    • dimorphism
    • yeast-mycelium transition

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