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Induction of the Keapl/Nrf2/ARE pathway by oxidizable diphenols
Albena T. Dinkova-Kostova
, Xiu Jun Wang
Research output
:
Contribution to journal
›
Article
›
peer-review
69
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Citations (Scopus)
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Keyphrases
Inducer
100%
Hydroquinone
100%
Keapl
100%
Oxidizable
100%
Cu2+
100%
Tert-butyl
100%
Diphenol
100%
Nrf2-ARE Pathway
100%
Ortho
75%
Quinones
75%
Kelch-like ECH-associated Protein 1 (Keap1)
50%
Cysteine Residues
50%
Electrophilic
50%
Keap1-Nrf2 Pathway
50%
1,4-Hydroquinone
50%
1,4-quinones
50%
Hypoxia
25%
Small Molecules
25%
Electrophile
25%
Multicellular Organism
25%
Dopamine
25%
Potentiation
25%
Electron Affinity
25%
Catechol Estrogens
25%
Lability
25%
Two-step Mechanism
25%
L-DOPA
25%
Luciferase
25%
Linear Correlation
25%
Molecular Orbital Calculations
25%
Sensor Protein
25%
Quinone Derivatives
25%
Reporter Cell Line
25%
Pharmacology, Toxicology and Pharmaceutical Science
Transcription Factor Nrf2
100%
Cuprous Ion
100%
Hydroquinone Derivative
66%
Cysteine
33%
Hydroquinone
33%
Hypoxia
16%
Oxidizing Agent
16%
Electrophile
16%
Cytoprotective Agent
16%
Quinone Derivative
16%
DOPA
16%
Luciferase
16%
Transition Element
16%
Catechol Estrogen
16%
Molecular Orbital
16%
Electron Affinity
16%
Dopamine
16%