Inflammatory bowel disease

Richard Hansen, Fiona Louise Cameron, Georgina Louise Hold, Emad Munir El-Omar, Richard Kay Russell

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


Inflammatory bowel disease (IBD) describes a heterogeneous group of chronic inflammatory diseases of the gastrointestinal tract, of which Crohn's disease and ulcerative colitis are the most common diagnoses. About a quarter of IBD presents in childhood, and the phenotype seen involves a wider disease distribution in both Crohn's and ulcerative colitis than seen in adult-onset disease. The incidence of IBD appears to be rising and although we understand more about the genetic, immunological and environmental contributors to aetiology, we do not yet fully understand this rise. In paediatric practice, IBD and in particular Crohn's disease, often results in impaired weight gain, poor linear growth and delayed puberty. Multiple treatment modalities exist for IBD from longstanding treatments such as steroids and immunosuppressants to modern, targeted therapies such as infliximab. This review discusses the current state of the art of clinical practice in relation to paediatric IBD.

Original languageEnglish
Pages (from-to)473-478
Number of pages6
JournalPaediatrics and Child Health
Issue number10
Publication statusPublished - Oct 2010


  • Children
  • Crohn's disease
  • Inflammatory bowel disease
  • Treatment
  • Ulcerative colitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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