Inhibition, rather than activation, of p38 accounts for the cardioprotective effect of ischaemic preconditioning

Keyphrases

• Protein Kinase 100%
• Cardioprotection 100%
• Ischemic Preconditioning 100%
• Ischemia 90%
• Mitogen-activated Protein Kinase 50%
• P38 Activation 50%
• Active Protein 40%
• Myocytes 30%
• Constitutively Active 20%
• Overexpressing 20%
• Kinase Family 20%
• Cell Death 10%
• One-group 10%
• Signaling Molecules 10%
• Signaling Cascades 10%
• Attenuation 10%
• Kinase Activation 10%
• SB203580 10%
• Phosphorylation 10%
• Pharmacological Inhibitors 10%
• Neonatal Rat Cardiomyocytes 10%
• Cellular Stress Response 10%
• Basal Level 10%
• Genetic Manipulation 10%
• Negative Regulation 10%
• Protection Level 10%
• Stress Signaling 10%
• Deleterious Effects 10%
• Common Mechanisms 10%
• P38α 10%
• Regulatory Proteins 10%
• Adenoviral 10%
• Kinase Phosphorylation 10%
• Myocardial Protection 10%
• Surrogate Model 10%
• Simulated Ischemia 10%
• Deoxygenation 10%

Immunology and Microbiology

• Ischemic Preconditioning 100%
• Protein Kinase C 100%
• Mitogen 50%
• Muscle Cell 30%
• Cell Death 10%
• Cellular Stress Response 10%
• Genetic Transfection 10%
• Cardiac Muscle Cell 10%
• Isotype 10%
• Genetic Manipulation 10%
• Reoxygenation 10%

Biochemistry, Genetics and Molecular Biology

• Protein Kinase C 100%
• Ischemic Preconditioning 100%
• Mitogen-Activated Protein Kinase 50%
• Cell Death 10%
• Transfection 10%
• Phosphotransferase 10%
• Kinase 10%
• Cardiac Muscle Cell 10%
• Cellular Stress Response 10%
• Genetic Manipulation 10%
• Lactate Dehydrogenase 10%
• Reoxygenation 10%