Insight from the air-skin interface

Ryan F. L. O'Shaughnessy; Sara J. Brown

doi:10.1038/jid.2014.457

Insight from the air-skin interface

Ryan F. L. O'Shaughnessy, Sara J. Brown (Lead / Corresponding author)

Research output: Contribution to journal › Comment/debate › peer-review

4 Citations (Scopus)

Abstract

The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin.

Original language	English
Pages (from-to)	331-333
Number of pages	3
Journal	Journal of Investigative Dermatology
Volume	135
Issue number	2
DOIs	https://doi.org/10.1038/jid.2014.457
Publication status	Published - Feb 2015

ASJC Scopus subject areas

General Medicine

Access to Document

10.1038/jid.2014.457

Cite this

@article{16c7fc58155d459bb03aacf8cc36f1d4,

title = "Insight from the air-skin interface",

abstract = "The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin. ",

author = "O'Shaughnessy, {Ryan F. L.} and Brown, {Sara J.}",

year = "2015",

month = feb,

doi = "10.1038/jid.2014.457",

language = "English",

volume = "135",

pages = "331--333",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Insight from the air-skin interface

AU - O'Shaughnessy, Ryan F. L.

AU - Brown, Sara J.

PY - 2015/2

Y1 - 2015/2

N2 - The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin.

AB - The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin.

UR - http://www.scopus.com/inward/record.url?scp=84925366363&partnerID=8YFLogxK

U2 - 10.1038/jid.2014.457

DO - 10.1038/jid.2014.457

M3 - Comment/debate

C2 - 25573043

AN - SCOPUS:84925366363

SN - 0022-202X

VL - 135

SP - 331

EP - 333

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - 2

ER -

Insight from the air-skin interface

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this