Insight from the air-skin interface

Ryan F. L. O'Shaughnessy, Sara J. Brown (Lead / Corresponding author)

    Research output: Contribution to journalComment/debate

    2 Citations (Scopus)

    Abstract

    The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin.

    Original languageEnglish
    Pages (from-to)331-333
    Number of pages3
    JournalJournal of Investigative Dermatology
    Volume135
    Issue number2
    DOIs
    Publication statusPublished - Feb 2015

    Fingerprint

    Skin
    Air
    Epidermis
    Tissue
    Proteins
    Hypoxia
    filaggrin

    Cite this

    O'Shaughnessy, Ryan F. L. ; Brown, Sara J. / Insight from the air-skin interface. In: Journal of Investigative Dermatology. 2015 ; Vol. 135, No. 2. pp. 331-333.
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    title = "Insight from the air-skin interface",
    abstract = "The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin.",
    author = "O'Shaughnessy, {Ryan F. L.} and Brown, {Sara J.}",
    year = "2015",
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    Insight from the air-skin interface. / O'Shaughnessy, Ryan F. L.; Brown, Sara J. (Lead / Corresponding author).

    In: Journal of Investigative Dermatology, Vol. 135, No. 2, 02.2015, p. 331-333.

    Research output: Contribution to journalComment/debate

    TY - JOUR

    T1 - Insight from the air-skin interface

    AU - O'Shaughnessy, Ryan F. L.

    AU - Brown, Sara J.

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    AB - The epidermis is a relatively hypoxic tissue, despite being continually exposed to air. The role of hypoxia in epidermal differentiation and skin barrier function is incompletely understood. In this issue, Wong et al. show that hypoxia-inducible factors are central to the processes of epidermal differentiation and barrier formation, in particular by promoting the expression of the key skin barrier protein filaggrin.

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    U2 - 10.1038/jid.2014.457

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    M3 - Comment/debate

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    JO - Journal of Investigative Dermatology

    JF - Journal of Investigative Dermatology

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