Intra- and interobserver variability of novel magnetic resonance imaging parameters for hip screening and treatment outcomes at age 5 years

A. Graham Wilkinson (Lead / Corresponding author), Sally Wilkinson, Robert A. Elton, Rachael R. Kirkbride, Thomas Foster, Freya Johnson, Sarah Zycinski, Lianne Boyce, Neil G. McIntyre, Simon F. McGurk, Kaseem A. Ajilogba

Research output: Contribution to journalArticlepeer-review


Background: The outcome measure of neonatal hip screening is usually the radiographic acetabular index. Objective: To assess the feasibility of magnetic resonance imaging (MRI) without sedation and compare the utility of outcome parameters measured from MRI images.

Materials and methods: The invitation for MRI scanning at 5 years of age was incorporated into follow-up for babies who had more than one ultrasound examination during treatment or surveillance.

Results: Diagnostic images were obtained in 132 of 134 children. The mean osseous acetabular index (standard deviation [SD]) was 16.6 (3.3) degrees for the right hip and 17.8 (3.2) for the left; the values for the cartilaginous acetabular index were 3.1 (3) and 3.4 (3.2). The mean downslope of a tangent to the lateral bony acetabular roof was 10.4 (4.5) and 9.0 (4.3) with respect to Hilgenreiner’s line and that of a line drawn through the apex to the margin of the acetabulum was 3.7 (4.6) and 3.9 (4.7). Intra- and interobserver variation was greater for measures specific to the lateral acetabular roof than for ossific and cartilaginous indices. There was significant negative correlation between the downslope of the tangent to the lateral roof index and the age at onset of treatment on both sides, but no significant correlation for ossific or cartilaginous acetabular indices or apex-marginal index.

Conclusion: MRI without sedation at 5 years of age is feasible as an outcome measure for hip screening programmes. Parameters specific to the lateral acetabulum may better reflect acetabular sufficiency, despite having greater observer variation than cartilaginous and ossific acetabular indices.

Original languageEnglish
Pages (from-to)415-425
Number of pages11
JournalPediatric Radiology
Early online date9 Jan 2023
Publication statusPublished - Mar 2023


  • Children
  • Developmental dysplasia of the hip
  • Magnetic resonance imaging
  • Screening

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging


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