Intraepithelial T cells move from gut to breast to shape lactation

Amanpreet Chawla; Mahima Swamy

doi:10.1038/s41590-025-02221-8

Intraepithelial T cells move from gut to breast to shape lactation

Amanpreet Chawla
, Mahima Swamy (Lead / Corresponding author)

MRC PPU

Research output: Contribution to journal › Comment/debate › peer-review

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Abstract

During late gestation, unconventional intraepithelial αβ T cells migrate from the gut to the mammary gland to remodel the tissue for lactation and enhance its mucosal barrier state.

Original language	English
Pages (from-to)	1219–1220
Number of pages	2
Journal	Nature Immunology
Volume	26
Issue number	8
Early online date	29 Jul 2025
DOIs	https://doi.org/10.1038/s41590-025-02221-8
Publication status	Published - Aug 2025

Keywords

Immunology
Lymphocytes
Mucosal immunology

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1038/s41590-025-02221-8

Author Accepted ManuscriptAccepted author manuscript, 996 KBLicence: Other

Cite this

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title = "Intraepithelial T cells move from gut to breast to shape lactation",

abstract = "During late gestation, unconventional intraepithelial αβ T cells migrate from the gut to the mammary gland to remodel the tissue for lactation and enhance its mucosal barrier state.",

keywords = "Immunology, Lymphocytes, Mucosal immunology",

author = "Amanpreet Chawla and Mahima Swamy",

year = "2025",

month = aug,

doi = "10.1038/s41590-025-02221-8",

language = "English",

volume = "26",

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AU - Chawla, Amanpreet

AU - Swamy, Mahima

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N2 - During late gestation, unconventional intraepithelial αβ T cells migrate from the gut to the mammary gland to remodel the tissue for lactation and enhance its mucosal barrier state.

AB - During late gestation, unconventional intraepithelial αβ T cells migrate from the gut to the mammary gland to remodel the tissue for lactation and enhance its mucosal barrier state.

KW - Immunology

KW - Lymphocytes

KW - Mucosal immunology

U2 - 10.1038/s41590-025-02221-8

DO - 10.1038/s41590-025-02221-8

M3 - Comment/debate

C2 - 40730898

SN - 1529-2908

VL - 26

SP - 1219

EP - 1220

JO - Nature Immunology

JF - Nature Immunology

IS - 8

ER -

Intraepithelial T cells move from gut to breast to shape lactation

Abstract

Keywords

ASJC Scopus subject areas

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