Intronic noncoding RNAs and splicing

John W. S. Brown, David F. Marshall, Manuel Echeverria

    Research output: Contribution to journalArticlepeer-review

    102 Citations (Scopus)

    Abstract

    The gene organization of small nucleolar RNAs (snoRNAs) and microRNAs (miRNAs) varies within and among different organisms. This diversity is reflected in the maturation pathways of these small noncoding RNAs (ncRNAs). The presence of noncoding RNAs in introns has implications for the biogenesis of both mature small RNAs and host mRNA. The balance of the interactions between the processing or ribonucleoprotein assembly of intronic noncoding RNAs and the splicing process can regulate the levels of ncRNA and host mRNA. The processing of snoRNAs - both intronic and non-intronic - is well characterised in yeast, plants and animals and provides a basis for examining how intronic plant miRNAs are processed.
    Original languageEnglish
    Pages (from-to)335-342
    Number of pages8
    JournalTrends in Plant Science
    Volume13
    Issue number7
    DOIs
    Publication statusPublished - 2008

    Fingerprint Dive into the research topics of 'Intronic noncoding RNAs and splicing'. Together they form a unique fingerprint.

    Cite this