IPASC: A community-driven consensus-based initiative towards standardisation in photoacoustic imaging

Sarah E. Bohndiek, Ben Cox, James Joseph, Janek Grohl, Lina Hacker, Stefan Morscher, William C. Vogt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Photoacoustic Imaging (PAI) is a rapidly emerging imaging modality that is based on the conversion from light into ultrasound. One of the most promising applications of PAI is in diagnosis and longitudinal monitoring of solid tumours. By visualizing differences in the optical energy absorbed by endogenous chromophores, such as haemoglobin or melanin, PAI has made rapid advances over the past decade. In particular, PAI has been successfully demonstrated in early stage human trials in cancer, for delineating benign and malignant lesions as well as monitoring treatment. The promise of these early pilot studies has led to the development of several commercial clinical PAI instruments. Furthermore, qualitative image interpretation is increasingly being replaced by calculation of quantitative imaging biomarkers (IBs) as both research tools and as putative clinical decision-making tools. Considering the recently reported roadmaps for clinical translation of IBs, it is clear that acceleration of PAI biomarkers into clinical use requires parallel technical, biological and clinical validation, as well as assessment of cost-effectiveness. The International Photoacoustic Standardisation Consortium (IPASC) has been founded to address this unmet need. The overall objective of IPASC is to reach an international consensus on PAI standardization to improve the quality of preclinical studies and to accelerate efforts in clinical translation.

Original languageEnglish
Title of host publicationIUS 2020 - International Ultrasonics Symposium, Proceedings
PublisherIEEE
Number of pages4
ISBN (Electronic)9781728154480
ISBN (Print)9781728154497
DOIs
Publication statusPublished - 17 Nov 2020
Event2020 IEEE International Ultrasonics Symposium, IUS 2020 - Las Vegas, United States
Duration: 7 Sep 202011 Sep 2020

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2020-September
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2020 IEEE International Ultrasonics Symposium, IUS 2020
CountryUnited States
CityLas Vegas
Period7/09/2011/09/20

Keywords

  • Phantoms
  • Photoacoustics
  • Standardisation

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