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Abstract
There is a growing understanding that the early phases of type 1 diabetes (T1D) are characterised by a deleterious dialogue between the pancreatic beta cells and the immune system. This, combined with the urgent need to better translate this growing knowledge into novel therapies, provided the background for the JDRF-DiabetesUK-INNODIA-nPOD symposium entitled 'Islet cells in human T1D: from recent advances to novel therapies', which took place in Stockholm, Sweden, in September 2022. We provide in this article an overview of the main themes addressed in the symposium, pointing to both promising conclusions and key unmet needs that remain to be addressed in order to achieve better approaches to prevent or reverse T1D.
Original language | English |
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Article number | e230082 |
Number of pages | 20 |
Journal | Journal of Endocrinology |
Volume | 259 |
Issue number | 1 |
Early online date | 26 Jul 2023 |
DOIs | |
Publication status | Published - 31 Aug 2023 |
Keywords
- islet
- pancreas
- insulin secretion
- autoimmune
- diabetes
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
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- 2 Active
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Development of Therapeutic Strategies to Regenerate Pancreatic Beta Cells: Towards a Disease-Modifying Treatment for Type 1 Diabetes
Cantley, J. (Investigator)
24/04/23 → 16/07/28
Project: Research