Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites

Keyphrases

• Drug Discovery 100%
• Non-mevalonate Pathway 100%
• Apicomplexan Parasites 100%
• Isoprenoid Compounds 100%
• Biological Processes 33%
• Enzyme Catalysis 33%
• Large Families 33%
• Malaria 33%
• Orthologues 33%
• Gram-negative Bacteria 33%
• Structural Information 33%
• Natural Products 33%
• Metal Ions 33%
• Biosynthetic Pathway 33%
• Apicomplexan 33%
• Human Disease 33%
• Diphosphate 33%
• Program Targeting 33%
• Mevalonate 33%
• Plasmodium 33%
• Parasitic Diseases 33%
• Plant Chloroplast 33%
• Mechanistic Data 33%
• Human Use 33%
• Bacterial Enzymes 33%
• Isoprenoids 33%
• New Drug Development 33%
• Veterinary Importance 33%
• Isopentenyl Diphosphate 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Drug Discovery 100%
• Mevalonic Acid 100%
• Isoprenoid 100%
• Apicomplexa 100%
• Diseases 100%
• Infectious Agent 25%
• Plasmodium 25%
• Natural Product 25%
• Infection 25%
• Gram Negative Bacterium 25%
• Pyrophosphate 25%
• Isopentenyl Diphosphate 25%
• Bacterial Enzyme 25%
• Metal Ion 25%

Biochemistry, Genetics and Molecular Biology

• Precursor 100%
• Anabolism 100%
• Apicomplexa 100%
• Enzyme 75%
• Non-Mevalonate Pathway 75%
• Pyrophosphate 50%
• Biological Phenomena and Functions Concerning the Entire Organism 25%
• Genetics 25%
• Chloroplast 25%
• Infectious Agent 25%
• Gram Negative Bacterium 25%
• Plasmodium 25%