Isosteres of nucleoside triphosphates

Richard Weaver, Ian H. Gilbert, Naheed Mahmood, Jan Balzarini

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    Abstract

    This paper describes the design and synthesis of lipophilic isosteres of nucleoside triphosphates as potential inhibitors of HIV reverse transcriptase. The isosteric replacement of the triphosphate group is a modification of the citrate group. Copyright (C) 1996 Elsevier Science Ltd.

    Original languageEnglish
    Pages (from-to)2405-2410
    Number of pages6
    JournalBioorganic & Medicinal Chemistry Letters
    Volume6
    Issue number20
    DOIs
    Publication statusPublished - 22 Oct 1996

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