Isosteres of nucleoside triphosphates

Richard Weaver; Ian H.  Gilbert; Naheed  Mahmood; Jan Balzarini

doi:10.1016/0960-894X(96)00444-1

Isosteres of nucleoside triphosphates

Richard Weaver
, Ian H. Gilbert
, Naheed Mahmood
, Jan Balzarini

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

This paper describes the design and synthesis of lipophilic isosteres of nucleoside triphosphates as potential inhibitors of HIV reverse transcriptase. The isosteric replacement of the triphosphate group is a modification of the citrate group. Copyright (C) 1996 Elsevier Science Ltd.

Original language	English
Pages (from-to)	2405-2410
Number of pages	6
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	6
Issue number	20
DOIs	https://doi.org/10.1016/0960-894X(96)00444-1
Publication status	Published - 22 Oct 1996

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/0960-894X(96)00444-1

Cite this

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title = "Isosteres of nucleoside triphosphates",

abstract = "This paper describes the design and synthesis of lipophilic isosteres of nucleoside triphosphates as potential inhibitors of HIV reverse transcriptase. The isosteric replacement of the triphosphate group is a modification of the citrate group. Copyright (C) 1996 Elsevier Science Ltd.",

author = "Richard Weaver and Gilbert, \{Ian H.\} and Naheed Mahmood and Jan Balzarini",

year = "1996",

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T1 - Isosteres of nucleoside triphosphates

AU - Weaver, Richard

AU - Gilbert, Ian H.

AU - Mahmood, Naheed

AU - Balzarini, Jan

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AB - This paper describes the design and synthesis of lipophilic isosteres of nucleoside triphosphates as potential inhibitors of HIV reverse transcriptase. The isosteric replacement of the triphosphate group is a modification of the citrate group. Copyright (C) 1996 Elsevier Science Ltd.

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DO - 10.1016/0960-894X(96)00444-1

M3 - Article

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VL - 6

SP - 2405

EP - 2410

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

IS - 20

ER -

Isosteres of nucleoside triphosphates

Abstract

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