ZNF804A and cortical thickness in schizophrenia and bipolar disorder

Orjan Bergmann; Unn K. Haukvik; Andrew A Brown; Lars M. Rimol; Cecilie B. Hartberg; Lavinia Athanasiu; Ingrid Melle; Srdjan Djurovic; Ole A. Andreassen; Anders M. Dale; Ingrid Agartz

doi:10.1016/j.pscychresns.2013.01.007

ZNF804A and cortical thickness in schizophrenia and bipolar disorder

Orjan Bergmann, Unn K. Haukvik, Andrew A Brown, Lars M. Rimol, Cecilie B. Hartberg, Lavinia Athanasiu, Ingrid Melle, Srdjan Djurovic, Ole A. Andreassen, Anders M. Dale, Ingrid Agartz

Population Health and Genomics

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

ZNF804A SNP rs1344706 confers genome-wide risk for schizophrenia and bipolar disorder. Both disorders affect cortical thickness. To determine if single nucleotide polymorphisms (SNPs) across ZNF804A are associated with cortical thinning, we investigated 63 SNPs (including rs1344706) in 365 psychosis patients and healthy controls. Results show no significant associations.

Original language	English
Pages (from-to)	154-157
Number of pages	4
Journal	Psychiatry Research
Volume	212
Issue number	2
DOIs	https://doi.org/10.1016/j.pscychresns.2013.01.007
Publication status	Published - 30 May 2013

Keywords

Adult
Bipolar Disorder/genetics
Cerebral Cortex/pathology
Female
Gene Frequency
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans
Image Processing, Computer-Assisted
Kruppel-Like Transcription Factors/genetics
Magnetic Resonance Imaging
Male
Middle Aged
Polymorphism, Single Nucleotide/genetics
Schizophrenia/genetics
Young Adult

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10.1016/j.pscychresns.2013.01.007

Cite this

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title = "ZNF804A and cortical thickness in schizophrenia and bipolar disorder",

abstract = "ZNF804A SNP rs1344706 confers genome-wide risk for schizophrenia and bipolar disorder. Both disorders affect cortical thickness. To determine if single nucleotide polymorphisms (SNPs) across ZNF804A are associated with cortical thinning, we investigated 63 SNPs (including rs1344706) in 365 psychosis patients and healthy controls. Results show no significant associations.",

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year = "2013",

month = may,

day = "30",

doi = "10.1016/j.pscychresns.2013.01.007",

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T1 - ZNF804A and cortical thickness in schizophrenia and bipolar disorder

AU - Bergmann, Orjan

AU - Haukvik, Unn K.

AU - Brown, Andrew A

AU - Rimol, Lars M.

AU - Hartberg, Cecilie B.

AU - Athanasiu, Lavinia

AU - Melle, Ingrid

AU - Djurovic, Srdjan

AU - Andreassen, Ole A.

AU - Dale, Anders M.

AU - Agartz, Ingrid

PY - 2013/5/30

Y1 - 2013/5/30

N2 - ZNF804A SNP rs1344706 confers genome-wide risk for schizophrenia and bipolar disorder. Both disorders affect cortical thickness. To determine if single nucleotide polymorphisms (SNPs) across ZNF804A are associated with cortical thinning, we investigated 63 SNPs (including rs1344706) in 365 psychosis patients and healthy controls. Results show no significant associations.

AB - ZNF804A SNP rs1344706 confers genome-wide risk for schizophrenia and bipolar disorder. Both disorders affect cortical thickness. To determine if single nucleotide polymorphisms (SNPs) across ZNF804A are associated with cortical thinning, we investigated 63 SNPs (including rs1344706) in 365 psychosis patients and healthy controls. Results show no significant associations.

KW - Adult

KW - Bipolar Disorder/genetics

KW - Cerebral Cortex/pathology

KW - Female

KW - Gene Frequency

KW - Genetic Predisposition to Disease

KW - Genome-Wide Association Study

KW - Genotype

KW - Humans

KW - Image Processing, Computer-Assisted

KW - Kruppel-Like Transcription Factors/genetics

KW - Magnetic Resonance Imaging

KW - Male

KW - Middle Aged

KW - Polymorphism, Single Nucleotide/genetics

KW - Schizophrenia/genetics

KW - Young Adult

U2 - 10.1016/j.pscychresns.2013.01.007

DO - 10.1016/j.pscychresns.2013.01.007

M3 - Article

C2 - 23562677

SN - 0165-1781

VL - 212

SP - 154

EP - 157

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2

ER -

ZNF804A and cortical thickness in schizophrenia and bipolar disorder

Abstract

Keywords

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