ZNF804A and cortical thickness in schizophrenia and bipolar disorder

Orjan Bergmann, Unn K. Haukvik, Andrew A Brown, Lars M. Rimol, Cecilie B. Hartberg, Lavinia Athanasiu, Ingrid Melle, Srdjan Djurovic, Ole A. Andreassen, Anders M. Dale, Ingrid Agartz

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

ZNF804A SNP rs1344706 confers genome-wide risk for schizophrenia and bipolar disorder. Both disorders affect cortical thickness. To determine if single nucleotide polymorphisms (SNPs) across ZNF804A are associated with cortical thinning, we investigated 63 SNPs (including rs1344706) in 365 psychosis patients and healthy controls. Results show no significant associations.

Original languageEnglish
Pages (from-to)154-157
Number of pages4
JournalPsychiatry Research
Volume212
Issue number2
DOIs
Publication statusPublished - 30 May 2013

Keywords

  • Adult
  • Bipolar Disorder/genetics
  • Cerebral Cortex/pathology
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Genome-Wide Association Study
  • Genotype
  • Humans
  • Image Processing, Computer-Assisted
  • Kruppel-Like Transcription Factors/genetics
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide/genetics
  • Schizophrenia/genetics
  • Young Adult

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  • Cite this

    Bergmann, O., Haukvik, U. K., Brown, A. A., Rimol, L. M., Hartberg, C. B., Athanasiu, L., Melle, I., Djurovic, S., Andreassen, O. A., Dale, A. M., & Agartz, I. (2013). ZNF804A and cortical thickness in schizophrenia and bipolar disorder. Psychiatry Research, 212(2), 154-157. https://doi.org/10.1016/j.pscychresns.2013.01.007