Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19

TY - JOUR

T1 - Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19

AU - Houchen-Wolloff, Linzy

AU - Poinasamy, Krisnah

AU - Holmes, Kate

AU - Tarpey, Maryrose

AU - Hastie, Claire

AU - Raihani, Kelly

AU - Rogers, Natalie

AU - Smith, Nikki

AU - Adams, Dawn

AU - Burgess, Paul

AU - Clark, Jean

AU - Cranage, Clare

AU - Desai, Mahadev

AU - Geary, Nicola

AU - Gill, Rhyan

AU - Mangwani, Jitendra

AU - Staunton, Lily

AU - Berry, Colin

AU - Bolton, Charlotte E.

AU - Chalder, Trudie

AU - Chalmers, James

AU - De Soyza, Anthony

AU - Elneima, Omer

AU - Geddes, John

AU - Heller, Simon

AU - Ho, Ling-Pei

AU - Jacob, Joseph

AU - McAuley, Hamish

AU - Parmar, Aarti

AU - Quint, Jennifer K.

AU - Raman, Betty

AU - Rowland, Matthew

AU - Singapuri, Amisha

AU - Singh, Sally J.

AU - Thomas, David

AU - Toshner, Mark R.

AU - Wain, Louise V.

AU - Horsley, Alex Robert

AU - Marks, Michael

AU - Brightling, Christopher E.

AU - Evans, Rachael A.

N1 - Funding Information: PHOSP-COVID is supported by a grant from the MRC-UK Research and Innovation and the Department of Health and Social Care through the National Institute for Health Research (NIHR) rapid response panel to tackle COVID-19 (grant references: MR/V027859/1 and COV0319). Core funding was provided by NIHR Leicester Biomedical Research Centre to support the PHOSP-COVID coordination team, and NIHR Biomedical Research Centres (BRCs), Clinical Research Facilities (CRF) and NIHR Health Protection Research Unit (HPRU) and Translational Research Collaborations (TRCs) network across the country. This research was funded in whole or in part by the Wellcome Trust [209553/Z/17/Z] for author JJ. RAE held a NIHR Clinical Scientist Fellowship CS-2016-16-020 during the conduct of the study © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

PY - 2022/7

Y1 - 2022/7

N2 - Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included: identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.

AB - Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included: identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.

KW - COVID-19

UR - https://www.scopus.com/pages/publications/85132427756

U2 - 10.1136/thoraxjnl-2021-218582

DO - 10.1136/thoraxjnl-2021-218582

M3 - Article

C2 - 35354642

SN - 0040-6376

VL - 77

SP - 717

EP - 720

JO - Thorax

JF - Thorax

IS - 7

ER -