JPred: a consensus secondary structure prediction server

J A Cuff, M E Clamp, A S Siddiqui, M Finlay, G J Barton

Research output: Contribution to journalArticle

885 Citations (Scopus)

Abstract

UNLABELLED: An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information from multiple sequences. A consensus prediction is also returned which improves the average Q3 accuracy of prediction by 1% to 72.9%. The server simplifies the use of current prediction algorithms and allows conservation patterns important to structure and function to be identified.

AVAILABILITY: http://barton.ebi.ac.uk/servers/jpred.h tml

CONTACT: geoff@ebi.ac.uk

Original languageEnglish
Pages (from-to)892-3
Number of pages2
JournalBioinformatics
Volume14
Issue number10
DOIs
Publication statusPublished - 1998

Keywords

  • Algorithms
  • Computational Biology
  • Consensus Sequence
  • Internet
  • Protein Structure, Secondary
  • Sequence Alignment
  • Software

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