Ketamine potentiates 5‐HT3 receptor‐mediated currents in rabbit nodose ganglion neurones

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Abstract

The interaction of ketamine with the 5‐HT3 receptor of rabbit nodose ganglion neurones is described. Ketamine (3–30 μm) enhanced 5‐HT3 receptor‐mediated currents recorded under voltage‐clamp conditions. This action did not appear to be related to the known effect of ketamine of inhibiting 5‐HT uptake. 1991 British Pharmacological Society

Original languageEnglish
Pages (from-to)1623-1625
Number of pages3
JournalBritish Journal of Pharmacology
Volume103
Issue number3
DOIs
Publication statusPublished - Jul 1991

Keywords

  • 5‐HT receptors
  • ketamine
  • rabbit nodose ganglion neurones

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