Ketamine potentiates 5‐HT3 receptor‐mediated currents in rabbit nodose ganglion neurones

John A. Peters; Hilary M. Malone; Jeremy J. Lambert

doi:10.1111/j.1476-5381.1991.tb09837.x

Ketamine potentiates 5‐HT₃ receptor‐mediated currents in rabbit nodose ganglion neurones

John A. Peters
, Hilary M. Malone
, Jeremy J. Lambert

DArcy Thompson Unit

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The interaction of ketamine with the 5‐HT₃ receptor of rabbit nodose ganglion neurones is described. Ketamine (3–30 μm) enhanced 5‐HT₃ receptor‐mediated currents recorded under voltage‐clamp conditions. This action did not appear to be related to the known effect of ketamine of inhibiting 5‐HT uptake. 1991 British Pharmacological Society

Original language	English
Pages (from-to)	1623-1625
Number of pages	3
Journal	British Journal of Pharmacology
Volume	103
Issue number	3
DOIs	https://doi.org/10.1111/j.1476-5381.1991.tb09837.x
Publication status	Published - Jul 1991

Keywords

5‐HT receptors
ketamine
rabbit nodose ganglion neurones

ASJC Scopus subject areas

Pharmacology

Access to Document

10.1111/j.1476-5381.1991.tb09837.x

Cite this

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title = "Ketamine potentiates 5‐HT3 receptor‐mediated currents in rabbit nodose ganglion neurones",

abstract = "The interaction of ketamine with the 5‐HT3 receptor of rabbit nodose ganglion neurones is described. Ketamine (3–30 μm) enhanced 5‐HT3 receptor‐mediated currents recorded under voltage‐clamp conditions. This action did not appear to be related to the known effect of ketamine of inhibiting 5‐HT uptake. 1991 British Pharmacological Society",

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AU - Malone, Hilary M.

AU - Lambert, Jeremy J.

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AB - The interaction of ketamine with the 5‐HT3 receptor of rabbit nodose ganglion neurones is described. Ketamine (3–30 μm) enhanced 5‐HT3 receptor‐mediated currents recorded under voltage‐clamp conditions. This action did not appear to be related to the known effect of ketamine of inhibiting 5‐HT uptake. 1991 British Pharmacological Society

KW - 5‐HT receptors

KW - ketamine

KW - rabbit nodose ganglion neurones

U2 - 10.1111/j.1476-5381.1991.tb09837.x

DO - 10.1111/j.1476-5381.1991.tb09837.x

M3 - Article

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