Knockout of ERK5 causes multiple defects in placental and embryonic development

Lijun Yan; Julia Carr; Peter R Ashby; Victoria Murray-Tait; Calum Thompson; J Simon C Arthur

doi:10.1186/1471-213X-3-11

Knockout of ERK5 causes multiple defects in placental and embryonic development

Lijun Yan, Julia Carr, Peter R Ashby, Victoria Murray-Tait, Calum Thompson, J Simon C Arthur

Research output: Contribution to journal › Article › peer-review

108 Citations (Scopus)

Abstract

ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear.

Original language	English
Number of pages	21
Journal	BMC Developmental Biology
Volume	3
DOIs	https://doi.org/10.1186/1471-213X-3-11
Publication status	Published - 16 Dec 2003

Keywords

Animals
Neovascularization, Physiologic
Head
Abdomen
Mice
Mice, Inbred BALB C
Mice, Knockout
Lower Extremity Deformities, Congenital
Mice, Inbred Strains
Lower Extremity
Gene Expression Regulation, Enzymologic
Mitogen-Activated Protein Kinase 7
Placenta
Mice, Inbred C57BL
Crosses, Genetic
Mitogen-Activated Protein Kinases
Embryo, Mammalian
Genes, Lethal
Mitogen-Activated Protein Kinase Kinases
Female
Gene Expression Regulation, Developmental
Male

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10.1186/1471-213X-3-11

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@article{cb62dc5b26f241918b978b21970637b0,

title = "Knockout of ERK5 causes multiple defects in placental and embryonic development",

abstract = "ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear.",

keywords = "Animals, Neovascularization, Physiologic, Head, Abdomen, Mice, Mice, Inbred BALB C, Mice, Knockout, Lower Extremity Deformities, Congenital, Mice, Inbred Strains, Lower Extremity, Gene Expression Regulation, Enzymologic, Mitogen-Activated Protein Kinase 7, Placenta, Mice, Inbred C57BL, Crosses, Genetic, Mitogen-Activated Protein Kinases, Embryo, Mammalian, Genes, Lethal, Mitogen-Activated Protein Kinase Kinases, Female, Gene Expression Regulation, Developmental, Male",

author = "Lijun Yan and Julia Carr and Ashby, {Peter R} and Victoria Murray-Tait and Calum Thompson and Arthur, {J Simon C}",

year = "2003",

month = dec,

day = "16",

doi = "10.1186/1471-213X-3-11",

language = "English",

volume = "3",

journal = "BMC Developmental Biology",

publisher = "Springer Verlag",

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TY - JOUR

T1 - Knockout of ERK5 causes multiple defects in placental and embryonic development

AU - Yan, Lijun

AU - Carr, Julia

AU - Ashby, Peter R

AU - Murray-Tait, Victoria

AU - Thompson, Calum

AU - Arthur, J Simon C

PY - 2003/12/16

Y1 - 2003/12/16

N2 - ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear.

AB - ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear.

KW - Animals

KW - Neovascularization, Physiologic

KW - Head

KW - Abdomen

KW - Mice

KW - Mice, Inbred BALB C

KW - Mice, Knockout

KW - Lower Extremity Deformities, Congenital

KW - Mice, Inbred Strains

KW - Lower Extremity

KW - Gene Expression Regulation, Enzymologic

KW - Mitogen-Activated Protein Kinase 7

KW - Placenta

KW - Mice, Inbred C57BL

KW - Crosses, Genetic

KW - Mitogen-Activated Protein Kinases

KW - Embryo, Mammalian

KW - Genes, Lethal

KW - Mitogen-Activated Protein Kinase Kinases

KW - Female

KW - Gene Expression Regulation, Developmental

KW - Male

U2 - 10.1186/1471-213X-3-11

DO - 10.1186/1471-213X-3-11

M3 - Article

C2 - 14675480

VL - 3

JO - BMC Developmental Biology

JF - BMC Developmental Biology

ER -

Knockout of ERK5 causes multiple defects in placental and embryonic development

Abstract

Keywords

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