Knockout of ERK5 causes multiple defects in placental and embryonic development

Lijun Yan, Julia Carr, Peter R Ashby, Victoria Murray-Tait, Calum Thompson, J Simon C Arthur

    Research output: Contribution to journalArticlepeer-review

    102 Citations (Scopus)


    ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear.

    Original languageEnglish
    Number of pages21
    JournalBMC Developmental Biology
    Publication statusPublished - 16 Dec 2003


    • Animals
    • Neovascularization, Physiologic
    • Head
    • Abdomen
    • Mice
    • Mice, Inbred BALB C
    • Mice, Knockout
    • Lower Extremity Deformities, Congenital
    • Mice, Inbred Strains
    • Lower Extremity
    • Gene Expression Regulation, Enzymologic
    • Mitogen-Activated Protein Kinase 7
    • Placenta
    • Mice, Inbred C57BL
    • Crosses, Genetic
    • Mitogen-Activated Protein Kinases
    • Embryo, Mammalian
    • Genes, Lethal
    • Mitogen-Activated Protein Kinase Kinases
    • Female
    • Gene Expression Regulation, Developmental
    • Male


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