Large sub-clonal variation in Phytophthora infestans from recent severe late blight epidemics in India

Tanmoy Dey, Amanda Saville, Kevin Myers, Susanta Tewari, David E. L. Cooke, Sucheta Tripathy, William E. Fry, Jean B. Ristaino, Sanjoy Guha Roy (Lead / Corresponding author)

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Abstract

The population structure of the Phytophthora infestans populations that caused the recent 2013-14 late blight epidemic in eastern India (EI) and northeastern India (NEI) was examined. The data provide new baseline information for populations of P. infestans in India. A migrant European 13_A2 genotype was responsible for the 2013-14 epidemic, replacing the existing populations. Mutations have generated substantial sub-clonal variation with 24 multi-locus genotypes (MLGs) found, of which 19 were unique variants not yet reported elsewhere globally. Samples from West Bengal were the most diverse and grouped alongside MLGs found in Europe, the UK and from neighbouring Bangladesh but were not linked directly to most samples from south India. The pathogen population was broadly more aggressive on potato than on tomato and resistant to the fungicide metalaxyl. Pathogen population diversity was higher in regions around the international borders with Bangladesh and Nepal. Overall, the multiple shared MLGs suggested genetic contributions from UK and Europe in addition to a sub-structure based on the geographical location within India. Our data indicate the need for improved phytosanitary procedures and continuous surveillance to prevent the further introduction of aggressive lineages of P. infestans into the country.

Original languageEnglish
Article number4429
Pages (from-to)1-12
Number of pages12
JournalScientific Reports
Volume8
DOIs
Publication statusPublished - 13 Mar 2018

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Phytophthora infestans
India
Genotype
Population
Bangladesh
Nepal
Lycopersicon esculentum
Solanum tuberosum
varespladib methyl
Mutation

Keywords

  • Journal article
  • Fungal host response
  • Microbe
  • Pathogens
  • Population dynamics
  • Rare variants

Cite this

Dey, T., Saville, A., Myers, K., Tewari, S., Cooke, D. E. L., Tripathy, S., ... Guha Roy, S. (2018). Large sub-clonal variation in Phytophthora infestans from recent severe late blight epidemics in India. Scientific Reports, 8, 1-12. [4429]. https://doi.org/10.1038/s41598-018-22192-1
Dey, Tanmoy ; Saville, Amanda ; Myers, Kevin ; Tewari, Susanta ; Cooke, David E. L. ; Tripathy, Sucheta ; Fry, William E. ; Ristaino, Jean B. ; Guha Roy, Sanjoy. / Large sub-clonal variation in Phytophthora infestans from recent severe late blight epidemics in India. In: Scientific Reports. 2018 ; Vol. 8. pp. 1-12.
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abstract = "The population structure of the Phytophthora infestans populations that caused the recent 2013-14 late blight epidemic in eastern India (EI) and northeastern India (NEI) was examined. The data provide new baseline information for populations of P. infestans in India. A migrant European 13_A2 genotype was responsible for the 2013-14 epidemic, replacing the existing populations. Mutations have generated substantial sub-clonal variation with 24 multi-locus genotypes (MLGs) found, of which 19 were unique variants not yet reported elsewhere globally. Samples from West Bengal were the most diverse and grouped alongside MLGs found in Europe, the UK and from neighbouring Bangladesh but were not linked directly to most samples from south India. The pathogen population was broadly more aggressive on potato than on tomato and resistant to the fungicide metalaxyl. Pathogen population diversity was higher in regions around the international borders with Bangladesh and Nepal. Overall, the multiple shared MLGs suggested genetic contributions from UK and Europe in addition to a sub-structure based on the geographical location within India. Our data indicate the need for improved phytosanitary procedures and continuous surveillance to prevent the further introduction of aggressive lineages of P. infestans into the country.",
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Dey, T, Saville, A, Myers, K, Tewari, S, Cooke, DEL, Tripathy, S, Fry, WE, Ristaino, JB & Guha Roy, S 2018, 'Large sub-clonal variation in Phytophthora infestans from recent severe late blight epidemics in India', Scientific Reports, vol. 8, 4429, pp. 1-12. https://doi.org/10.1038/s41598-018-22192-1

Large sub-clonal variation in Phytophthora infestans from recent severe late blight epidemics in India. / Dey, Tanmoy; Saville, Amanda; Myers, Kevin; Tewari, Susanta; Cooke, David E. L.; Tripathy, Sucheta; Fry, William E.; Ristaino, Jean B.; Guha Roy, Sanjoy (Lead / Corresponding author).

In: Scientific Reports, Vol. 8, 4429, 13.03.2018, p. 1-12.

Research output: Contribution to journalArticle

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AU - Dey, Tanmoy

AU - Saville, Amanda

AU - Myers, Kevin

AU - Tewari, Susanta

AU - Cooke, David E. L.

AU - Tripathy, Sucheta

AU - Fry, William E.

AU - Ristaino, Jean B.

AU - Guha Roy, Sanjoy

N1 - SGR, STr and TD acknowledge financial support from CSIR, New Delhi Grant Number 60(0108)/13/EMR-II. Funding for a portion of AS work from USDA AFRI Grant Number 2011-68004-30154. DC acknowledges financial support from the Scottish Government and AHDB Potatoes

PY - 2018/3/13

Y1 - 2018/3/13

N2 - The population structure of the Phytophthora infestans populations that caused the recent 2013-14 late blight epidemic in eastern India (EI) and northeastern India (NEI) was examined. The data provide new baseline information for populations of P. infestans in India. A migrant European 13_A2 genotype was responsible for the 2013-14 epidemic, replacing the existing populations. Mutations have generated substantial sub-clonal variation with 24 multi-locus genotypes (MLGs) found, of which 19 were unique variants not yet reported elsewhere globally. Samples from West Bengal were the most diverse and grouped alongside MLGs found in Europe, the UK and from neighbouring Bangladesh but were not linked directly to most samples from south India. The pathogen population was broadly more aggressive on potato than on tomato and resistant to the fungicide metalaxyl. Pathogen population diversity was higher in regions around the international borders with Bangladesh and Nepal. Overall, the multiple shared MLGs suggested genetic contributions from UK and Europe in addition to a sub-structure based on the geographical location within India. Our data indicate the need for improved phytosanitary procedures and continuous surveillance to prevent the further introduction of aggressive lineages of P. infestans into the country.

AB - The population structure of the Phytophthora infestans populations that caused the recent 2013-14 late blight epidemic in eastern India (EI) and northeastern India (NEI) was examined. The data provide new baseline information for populations of P. infestans in India. A migrant European 13_A2 genotype was responsible for the 2013-14 epidemic, replacing the existing populations. Mutations have generated substantial sub-clonal variation with 24 multi-locus genotypes (MLGs) found, of which 19 were unique variants not yet reported elsewhere globally. Samples from West Bengal were the most diverse and grouped alongside MLGs found in Europe, the UK and from neighbouring Bangladesh but were not linked directly to most samples from south India. The pathogen population was broadly more aggressive on potato than on tomato and resistant to the fungicide metalaxyl. Pathogen population diversity was higher in regions around the international borders with Bangladesh and Nepal. Overall, the multiple shared MLGs suggested genetic contributions from UK and Europe in addition to a sub-structure based on the geographical location within India. Our data indicate the need for improved phytosanitary procedures and continuous surveillance to prevent the further introduction of aggressive lineages of P. infestans into the country.

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