Lifestyle Changes in Women at Genetic Risk of Breast Cancer: an Observational Study

L. McLeish, M.M. Reis, C Stewart, D. R. Goudie, J. N. Berg, M. Harvie, K.A. Hanning, H. Vysny, C.M. Steel

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)


    Background: Lifestyle influences breast cancer risk. Women at increased familial risk may benefit from modifying behaviour, but it is not known to what extent they do so. Purpose: This study aims to measure changes that UK (Scottish) women make in response to increased familial risk of breast cancer and attitudes to a risk-reduction trial. Methods: A questionnaire, completed by 140 "breast cancer family" clinic patients, generated data on habitual diet, alcohol consumption and exercise, changes made after learning of breast cancer risk and attitudes to possible further changes. Subgroups of patients were defined by criteria likely to influence changes in behaviour. Between-group differences were analysed by Fisher's exact test and overall correlations by linear regression. Results: Thirty-six subjects (26 %) reported no behavioural change but, overall, around 25 % of diet, exercise and alcohol items had been changed. Women perceiving their lifetime cancer risk to be high (>50 %) and those who were obese (BMI >25) had made significantly more changes than others. Younger women (
    Original languageEnglish
    Pages (from-to)514-521
    Number of pages8
    JournalInternational Journal of Behavioral Medicine
    Issue number4
    Publication statusPublished - Dec 2012


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