Projects per year
Abstract
Purpose: Lifestyle interventions have been proposed to improve cancer survivorship in patients with colorectal cancer (CRC), but with treatment pathways becoming increasingly multi-modal and prolonged, opportunities for interventions may be limited. This systematic review assessed the evidence for the feasibility of performing lifestyle interventions in CRC patients and evaluated any short- and long-term health benefits.
Methods: Using PRISMA Guidelines, selected keywords identified randomised controlled studies (RCTs) of lifestyle interventions [smoking, alcohol, physical activity (PA), diet/ excess body weight] in CRC patients. These electronic databases were searched in June 2015: Dynamed, Cochrane Database, OVID MEDLINE, OVID EMBASE, PEDro.
Results: 14 RCTs were identified: PA RCTs (n=10) consisted mainly of telephone-prompted walking or cycling interventions of varied durations, predominately in adjuvant setting; dietary/ excess weight interventions RCTs (n=4) focused on low fat and/or high fibre diets within a multi-modal lifestyle intervention. There were no reported RCTs in smoking or alcohol cessation/ reduction. PA and/or dietary/ excess weight interventions reported variable recruitment rates, but good adherence and retention/ follow-up rates, leading to short-term improvements in dietary quality, physical, psychological and quality of life parameters. Only one study assessed long-term follow up, finding significantly improved cancer-specific survival after dietary intervention.
Conclusions: This is the first systematic review on lifestyle interventions in patients with CRC finding these interventions to be feasible with improvements in short-term health. Future work should focus on defining the optimal type of intervention (type, duration, timing, intensity) that not only leads to improved short-term outcomes, but also assesses long-term survival.
Methods: Using PRISMA Guidelines, selected keywords identified randomised controlled studies (RCTs) of lifestyle interventions [smoking, alcohol, physical activity (PA), diet/ excess body weight] in CRC patients. These electronic databases were searched in June 2015: Dynamed, Cochrane Database, OVID MEDLINE, OVID EMBASE, PEDro.
Results: 14 RCTs were identified: PA RCTs (n=10) consisted mainly of telephone-prompted walking or cycling interventions of varied durations, predominately in adjuvant setting; dietary/ excess weight interventions RCTs (n=4) focused on low fat and/or high fibre diets within a multi-modal lifestyle intervention. There were no reported RCTs in smoking or alcohol cessation/ reduction. PA and/or dietary/ excess weight interventions reported variable recruitment rates, but good adherence and retention/ follow-up rates, leading to short-term improvements in dietary quality, physical, psychological and quality of life parameters. Only one study assessed long-term follow up, finding significantly improved cancer-specific survival after dietary intervention.
Conclusions: This is the first systematic review on lifestyle interventions in patients with CRC finding these interventions to be feasible with improvements in short-term health. Future work should focus on defining the optimal type of intervention (type, duration, timing, intensity) that not only leads to improved short-term outcomes, but also assesses long-term survival.
Original language | English |
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Pages (from-to) | 765-775 |
Number of pages | 11 |
Journal | International Journal of Colorectal Disease |
Volume | 32 |
Issue number | 6 |
Early online date | 3 Apr 2017 |
DOIs | |
Publication status | Published - Jun 2017 |
Keywords
- Lifestyle interventions
- Colorectal cancer
- Patient outcomes
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Dive into the research topics of 'Lifestyle interventions are feasible in patients with colorectal cancer with potential short-term health benefits: a systematic review'. Together they form a unique fingerprint.Projects
- 1 Finished
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TreatWELL - A Feasibility Study to Assess the Delivery of a Lifestyle Intervention for Colorectal Cancer Patients Undergoing Potentially Curative Treatment (Joint with Universities of Stirling and Surrey)
Anderson, A. (Investigator), Campbell, A. (Investigator), Munro, A. (Investigator) & Steele, B. (Investigator)
1/12/13 → 30/06/15
Project: Research