Lipophilic bioisosteres of nucleoside triphosphates

Alastair O. Goldring, Ian H. Gilbert, Naheed Mahmood, Jan Balzarini

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)


    This paper describes the design and synthesis of lipophilic bioisosteres of nucleoside triphosphates as potential inhibitors of HIV reverse transcriptase. The bioisostere is designed to mimic the conformation of the nucleoside triphosphate when complexed to a metal ion such as magnesium. Copyright (C) 1996 Elsevier Science Ltd.

    Original languageEnglish
    Pages (from-to)2411-2416
    Number of pages6
    JournalBioorganic & Medicinal Chemistry Letters
    Issue number20
    Publication statusPublished - 22 Oct 1996


    Dive into the research topics of 'Lipophilic bioisosteres of nucleoside triphosphates'. Together they form a unique fingerprint.

    Cite this