Liquid biopsies in precision oncology for older adults with cancer

Yue Zhao; Jaime O Herrera-Caceres; Jennifer Nobes; ZiCheng Lyu; Marcus Vetter; Claire Falandry; Valentin Goede; Nina Rosa Neuendorff; Kah Poh Loh; Beverly Canin; Hans Wildiers; Nicolò Matteo Luca Battisti

doi:10.1038/s41698-026-01285-5

Liquid biopsies in precision oncology for older adults with cancer

Yue Zhao (Lead / Corresponding author)
, Jaime O Herrera-Caceres
, Jennifer Nobes
, ZiCheng Lyu
, Marcus Vetter
, Claire Falandry
, Valentin Goede
, Nina Rosa Neuendorff
, Kah Poh Loh
, Beverly Canin
, Hans Wildiers (Lead / Corresponding author)
, Nicolò Matteo Luca Battisti (Lead / Corresponding author)

Undergraduate Medicine

Research output: Contribution to journal › Review article › peer-review

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Abstract

As the global population ages, innovative strategies for cancer management in older adults are urgently needed. Liquid biopsy, a non-invasive tool, offers great promise for this demographic by enabling early detection, real-time monitoring, and therapeutic target identification. This review highlights the clinical utility, feasibility, and safety of liquid biopsies in geriatric oncology, emphasizing their potential integration into routine care to improve treatment outcomes and quality of life for older patients.

Original language	English
Article number	123
Journal	npj Precision Oncology
Volume	10
Early online date	5 Feb 2026
DOIs	https://doi.org/10.1038/s41698-026-01285-5
Publication status	Published - 19 Mar 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/s41698-026-01285-5Licence: CC BY

Final Published VersionFinal published version, 930 KBLicence: CC BY

Cite this

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abstract = "As the global population ages, innovative strategies for cancer management in older adults are urgently needed. Liquid biopsy, a non-invasive tool, offers great promise for this demographic by enabling early detection, real-time monitoring, and therapeutic target identification. This review highlights the clinical utility, feasibility, and safety of liquid biopsies in geriatric oncology, emphasizing their potential integration into routine care to improve treatment outcomes and quality of life for older patients.",

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T1 - Liquid biopsies in precision oncology for older adults with cancer

AU - Zhao, Yue

AU - Herrera-Caceres, Jaime O

AU - Nobes, Jennifer

AU - Lyu, ZiCheng

AU - Vetter, Marcus

AU - Falandry, Claire

AU - Goede, Valentin

AU - Neuendorff, Nina Rosa

AU - Loh, Kah Poh

AU - Canin, Beverly

AU - Wildiers, Hans

AU - Battisti, Nicolò Matteo Luca

PY - 2026/3/19

Y1 - 2026/3/19

N2 - As the global population ages, innovative strategies for cancer management in older adults are urgently needed. Liquid biopsy, a non-invasive tool, offers great promise for this demographic by enabling early detection, real-time monitoring, and therapeutic target identification. This review highlights the clinical utility, feasibility, and safety of liquid biopsies in geriatric oncology, emphasizing their potential integration into routine care to improve treatment outcomes and quality of life for older patients.

AB - As the global population ages, innovative strategies for cancer management in older adults are urgently needed. Liquid biopsy, a non-invasive tool, offers great promise for this demographic by enabling early detection, real-time monitoring, and therapeutic target identification. This review highlights the clinical utility, feasibility, and safety of liquid biopsies in geriatric oncology, emphasizing their potential integration into routine care to improve treatment outcomes and quality of life for older patients.

U2 - 10.1038/s41698-026-01285-5

DO - 10.1038/s41698-026-01285-5

M3 - Review article

C2 - 41644673

SN - 2397-768X

VL - 10

JO - npj Precision Oncology

JF - npj Precision Oncology

M1 - 123

ER -

Liquid biopsies in precision oncology for older adults with cancer

Abstract

UN SDGs

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