Location, location, location: identifying the neighborhoods of LPS signaling

Colin Watts

doi:10.1038/ni0408-343

Location, location, location: identifying the neighborhoods of LPS signaling

Colin Watts

Research output: Contribution to journal › Editorial › peer-review

29 Citations (Scopus)

Abstract

TLR4 somehow manages to activate both MyD88- and TRIF-dependent signaling. According to Medzhitovc and colleagues, TLR4 engages MyD88 and TRIF sequentially at the cell surface and in endosomes, respectively, thereby providing access to distinct pools of signaling proteins.

Original language	English
Pages (from-to)	343-345
Number of pages	3
Journal	Nature Immunology
Volume	9
Issue number	4
DOIs	https://doi.org/10.1038/ni0408-343
Publication status	Published - Apr 2008

Keywords

RECEPTOR
TRIF

Access to Document

10.1038/ni0408-343

Cite this

@article{2c882e05d95e40ea896eba6aa93aa4e3,

title = "Location, location, location: identifying the neighborhoods of LPS signaling",

abstract = "TLR4 somehow manages to activate both MyD88- and TRIF-dependent signaling. According to Medzhitovc and colleagues, TLR4 engages MyD88 and TRIF sequentially at the cell surface and in endosomes, respectively, thereby providing access to distinct pools of signaling proteins.",

keywords = "RECEPTOR, TRIF",

author = "Colin Watts",

year = "2008",

month = apr,

doi = "10.1038/ni0408-343",

language = "English",

volume = "9",

pages = "343--345",

journal = "Nature Immunology",

issn = "1529-2908",

publisher = "Nature Research",

number = "4",

}

TY - JOUR

T1 - Location, location, location

T2 - identifying the neighborhoods of LPS signaling

AU - Watts, Colin

PY - 2008/4

Y1 - 2008/4

N2 - TLR4 somehow manages to activate both MyD88- and TRIF-dependent signaling. According to Medzhitovc and colleagues, TLR4 engages MyD88 and TRIF sequentially at the cell surface and in endosomes, respectively, thereby providing access to distinct pools of signaling proteins.

AB - TLR4 somehow manages to activate both MyD88- and TRIF-dependent signaling. According to Medzhitovc and colleagues, TLR4 engages MyD88 and TRIF sequentially at the cell surface and in endosomes, respectively, thereby providing access to distinct pools of signaling proteins.

KW - RECEPTOR

KW - TRIF

U2 - 10.1038/ni0408-343

DO - 10.1038/ni0408-343

M3 - Editorial

C2 - 18349810

SN - 1529-2908

VL - 9

SP - 343

EP - 345

JO - Nature Immunology

JF - Nature Immunology

IS - 4

ER -

Location, location, location: identifying the neighborhoods of LPS signaling

Abstract

Keywords

Access to Document

Fingerprint

Cite this