Fluorescence light-sheet microscopy is increasingly adopted by developmental biologists to study how cells divide and differentiate to form organs and even entire organisms. The light-sheet microscope differs from a conventional microscope in that the specimen is illuminated by a plane of light orthogonal to the detection axis, thus keeping the out-of-focus areas dark while minimizing any potentially detrimental exposure of the sample. The light-sheet microscope has been found to be the ideal instrument for long-term and non-invasive studies of intact, and therefore three-dimensional, fluorescent samples.
|Number of pages||2|
|Publication status||Published - 4 Jun 2018|
|Event||Recent Trends in Charged Particle Optics and Surface Physics Instrumentation: 16th International Seminar - Skalský dvůr, Lhota, Czech Republic|
Duration: 4 Jun 2018 → 6 Jun 2018
Conference number: 16
|Conference||Recent Trends in Charged Particle Optics and Surface Physics Instrumentation|
|Period||4/06/18 → 6/06/18|
Vettenburg, T., Dalgarno, H. I. C., Nylk, J., Coll-Llado, C., Ferrier, D. E. K., Cizmar, T., Gunn-Moore, F. J., Dholakia, K., Corral, A., Rodriguez-Pulido, A., Flors, C., & Ripoll, J. (2018). Locking in on large volume light-sheet microscopy. 84-85. Abstract from Recent Trends in Charged Particle Optics and Surface Physics Instrumentation, Lhota, Czech Republic.