Longitudinal Multi-scale Mapping of Infant Cortical Folding using Spherical Wavelets

Dingna Duan, Islem Rekik, Shunren Xia, Weili Lin, John H. Gilmore, Dinggang Shen, Gang Li

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
184 Downloads (Pure)

Abstract

The dynamic development of brain cognition and motor functions during infancy are highly associated with the rapid changes of the convoluted cortical folding. However, little is known about how the cortical folding, which can be characterized on different scales, develops in the first two postnatal years. In this paper, we propose a curvature-based multi scale method using spherical wavelets to map the complicated longitudinal changes of cortical folding during infancy. Specifically, we first decompose the cortical curvature map, which encodes the cortical folding information, into multiple spatial-frequency scales, and then measure the scale-specific wavelet power at 6 different scales as quantitative indices of cortical folding degree. We apply this method on 219 longitudinal MR images from 73 healthy infants at 0, 1, and 2 years of age. We reveal that the changing patterns of cortical folding are both scale-specific and regionspecific. Particularly, at coarser spatial-frequency levels, the majority of the primary folds flatten out, while at finer spatial frequency levels, the majority of the minor folds become more convoluted. This study provides valuable insights into the longitudinal changes of infant cortical folding.
Original languageEnglish
Title of host publication2017 IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro
Place of PublicationUnited States
PublisherIEEE
Pages93-96
Number of pages4
ISBN (Print)9781509011735
DOIs
Publication statusPublished - 19 Jun 2017
EventIEEE International Symposium on Biomedical Imaging - Melbourne, Australia
Duration: 18 Apr 201721 Apr 2017
http://biomedicalimaging.org/2017/

Conference

ConferenceIEEE International Symposium on Biomedical Imaging
Abbreviated titleISBI
CountryAustralia
CityMelbourne
Period18/04/1721/04/17
Internet address

Keywords

  • Cortical folding
  • Infant
  • Longitudinal development
  • Spherical wavelets
  • Curvature

Fingerprint Dive into the research topics of 'Longitudinal Multi-scale Mapping of Infant Cortical Folding using Spherical Wavelets'. Together they form a unique fingerprint.

Cite this