Abstract
Plasma triglyceride levels are heritable and are correlated with the risk of coronary heart disease. Sequencing of the protein-coding regions of the human genome (the exome) has the potential to identify rare mutations that have a large effect on phenotype.
Original language | English |
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Pages (from-to) | 22-31 |
Number of pages | 10 |
Journal | New England Journal of Medicine |
Volume | 371 |
Issue number | 1 |
DOIs | |
Publication status | Published - 3 Jul 2014 |
Keywords
- African Continental Ancestry Group
- Apolipoprotein C-III
- Coronary Disease
- European Continental Ancestry Group
- Exome
- Genotype
- Heterozygote
- Humans
- Liver
- Mutation
- Risk Factors
- Sequence Analysis, DNA
- Triglycerides
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Profiles
-
Palmer, Colin
- Population Health and Genomics - Professor (Teaching and Research) & Personal Chair of Pharmacogenomics
Person: Academic