Abstract
Vav1 is a guanine nucleotide exchange factor that selectively activates the Rac1 GTPase and is expressed specifically in haematopoietic cells. Recent work has revealed how Vav1 integrates signals from lymphocyte antigen receptors and costimulatory receptors to control immune function.
| Original language | English |
|---|---|
| Pages (from-to) | R535-R538 |
| Number of pages | 4 |
| Journal | Current Biology |
| Volume | 8 |
| Issue number | 15 |
| Publication status | Published - 16 Jul 1998 |
ASJC Scopus subject areas
- General Biochemistry,Genetics and Molecular Biology
- General Agricultural and Biological Sciences