Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

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• Finished

  Institutional Strategic Support Fund (2016)

  Cantrell, D. (Investigator), Dinkova-Kostova, A. (Investigator), Kang, L. (Investigator), Murray, P. (Investigator) & Pearson, E. (Investigator)

  1/10/16 → 31/05/23

  Project: Research

  • Video Project 100%
  • Audio 100%
  • Dundee 89%
  • Life Sciences 42%
  • Growth Arrest 37%

• Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

  Fairlamb, A. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator) & Wyatt, P. (Investigator)

  1/01/15 → 31/12/20

  Project: Research

  • Visceral Leishmaniasis 100%
  • Drug Discovery 99%
  • Leishmania Donovani 82%
  • Chagas Disease 74%
  • Drug Target 69%

• State-of-the-Art Facilities for Structural Biology at the University of Dundee

  Hunter, B. (Investigator), Lilley, D. (Investigator), Owen-Hughes, T. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

  1/03/12 → 28/02/17

  Project: Research

  • Proteolysis Targeting chimera (PROTAC) 100%
  • Crystal Structure 82%
  • Protein Catabolism 71%
  • Enzyme 70%
  • Ligase 60%