Macrocyclic polyamine lactam synthesis by diphenyl ether closure of 23-, 24- And 28-membered rings

Simon Carrington; Ian S. Blagbrough; Alan H. Fairlamb

doi:10.1039/a806688d

Macrocyclic polyamine lactam synthesis by diphenyl ether closure of 23-, 24- And 28-membered rings

Simon Carrington
, Ian S. Blagbrough (Lead / Corresponding author)
, Alan H. Fairlamb

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Novel 23-, 24- and 28-membered cyclic polyamine amides (cinnamamides) have been prepared by closure of diphenyl ethers; functionalized conjugates of spermidine and spermine underwent intramolecular aromatic nucleophilic substitution to afford nitro-substituted analogues of cadabicine class (24-membered polyamine lactam) alkaloids.

Original language	English
Pages (from-to)	2335-2336
Number of pages	2
Journal	Chemical Communications
Issue number	21
DOIs	https://doi.org/10.1039/a806688d
Publication status	Published - 7 Nov 1998

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/a806688d

Cite this

@article{88d82a06a20e4e789257f7ad6dab2fae,

title = "Macrocyclic polyamine lactam synthesis by diphenyl ether closure of 23-, 24- And 28-membered rings",

abstract = "Novel 23-, 24- and 28-membered cyclic polyamine amides (cinnamamides) have been prepared by closure of diphenyl ethers; functionalized conjugates of spermidine and spermine underwent intramolecular aromatic nucleophilic substitution to afford nitro-substituted analogues of cadabicine class (24-membered polyamine lactam) alkaloids.",

author = "Simon Carrington and Blagbrough, \{Ian S.\} and Fairlamb, \{Alan H.\}",

year = "1998",

month = nov,

day = "7",

doi = "10.1039/a806688d",

language = "English",

pages = "2335--2336",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "21",

}

TY - JOUR

T1 - Macrocyclic polyamine lactam synthesis by diphenyl ether closure of 23-, 24- And 28-membered rings

AU - Carrington, Simon

AU - Blagbrough, Ian S.

AU - Fairlamb, Alan H.

PY - 1998/11/7

Y1 - 1998/11/7

N2 - Novel 23-, 24- and 28-membered cyclic polyamine amides (cinnamamides) have been prepared by closure of diphenyl ethers; functionalized conjugates of spermidine and spermine underwent intramolecular aromatic nucleophilic substitution to afford nitro-substituted analogues of cadabicine class (24-membered polyamine lactam) alkaloids.

AB - Novel 23-, 24- and 28-membered cyclic polyamine amides (cinnamamides) have been prepared by closure of diphenyl ethers; functionalized conjugates of spermidine and spermine underwent intramolecular aromatic nucleophilic substitution to afford nitro-substituted analogues of cadabicine class (24-membered polyamine lactam) alkaloids.

UR - https://www.scopus.com/pages/publications/0242498677

U2 - 10.1039/a806688d

DO - 10.1039/a806688d

M3 - Article

AN - SCOPUS:0242498677

SN - 1359-7345

SP - 2335

EP - 2336

JO - Chemical Communications

JF - Chemical Communications

IS - 21

ER -

Macrocyclic polyamine lactam synthesis by diphenyl ether closure of 23-, 24- And 28-membered rings

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this