In 2001 Rivers et al. published a landmark study in the New England Journal of Medicine showing that in a single centre, involving patients presenting to an emergency department with severe sepsis and septic shock, an early goal-directed therapy (EGDT) protocol significantly reduced mortality compared with those receiving usual care.1 This underpinned the long-standing tenet of medical practice that early detection and treatment of sepsis will reduce mortality.
|Number of pages||1|
|Journal||Journal of the Royal College of Physicians of Edinburgh|
|Publication status||Published - 2014|