Male contraceptive development: A medicinal chemistry perspective

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There is a need for non-hormonal contraceptives. One area that needs further investigation is the development of male contraceptives. Comparatively little is understood about potential drug targets in men to achieve a reversible contraceptive effect. In this article, we review the need for male contraceptives and some thoughts around the characteristics of a male contraceptive and the potential development pathway. We then discuss different potential approaches to discovering male contraceptives and then highlight potential targets that have been discussed in the literature.
Original languageEnglish
Article number114709
Pages (from-to)1-8
Number of pages8
JournalEuropean Journal of Medicinal Chemistry
Early online date25 Aug 2022
Publication statusPublished - 5 Dec 2022


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