TY - JOUR
T1 - Male obesity
T2 - impact on fertility
AU - Kay, Vanessa J.
AU - Barratt, Chritopher L. R.
N1 - Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Obesity has been shown to adversely affect male fertility, by reducing spermatogenesis. There are several aetiological theories including endocrine abnormalities, genetic, sexual dysfunction and testicular hyperthermia. Of these, endocrine abnormalities are likely to be the most important, involving increased oestrogen and increased insulin resistance, reduced androgens and reduced inhibin B levels. Possible management options include weight reduction by dieting or surgery and medical treatment to correct specific endocrine abnormalities, but as yet none has been proven to be effective.
AB - Obesity has been shown to adversely affect male fertility, by reducing spermatogenesis. There are several aetiological theories including endocrine abnormalities, genetic, sexual dysfunction and testicular hyperthermia. Of these, endocrine abnormalities are likely to be the most important, involving increased oestrogen and increased insulin resistance, reduced androgens and reduced inhibin B levels. Possible management options include weight reduction by dieting or surgery and medical treatment to correct specific endocrine abnormalities, but as yet none has been proven to be effective.
UR - http://www.scopus.com/inward/record.url?scp=74549178478&partnerID=8YFLogxK
U2 - 10.1177/1474651409343132
DO - 10.1177/1474651409343132
M3 - Article
AN - SCOPUS:74549178478
SN - 1474-6514
VL - 9
SP - 237
EP - 241
JO - The British Journal of Diabetes & Vascular Disease
JF - The British Journal of Diabetes & Vascular Disease
IS - 5
ER -
