Management of noncardiac comorbidities in chronic heart failure

Vun Heng Chong (Lead / Corresponding author), Jagdeep Singh, Helen Parry, Jocelyn Saunders, Farhad Chowdhury, Donna M. Mancini, Chim C. Lang

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Prevalence of heart failure is increasing, especially in the elderly population. Noncardiac comorbidities complicate heart failure care and are increasingly common in elderly patients with reduced or preserved ejection fraction heart failure, owing to prolongation of patient's lives by advances in chronic heart failure (CHF) management. Common comorbidities include respiratory disease, renal dysfunction, anemia, arthritis, obesity, diabetes mellitus, cognitive dysfunction, and depression. These conditions contribute to the progression of the disease and may alter the response to treatment, partly as polypharmacy is inevitable in these patients. Cardiologists and other physicians caring for patients with CHF need to be vigilant to comorbid conditions that complicate the care of these patients. There is now more guidance on management of noncardiac comorbidities in heart failure, and this article contains a comprehensive review of the most recent updates on management of noncardiac comorbidities in CHF.

Original languageEnglish
Pages (from-to)300-315
Number of pages16
JournalCardiovascular Therapeutics
Issue number5
Publication statusPublished - Oct 2015


  • Comorbidities
  • Drug treatment
  • Heart failure
  • Management

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)
  • Pharmacology


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