Projects per year
Mannose-binding lectin (MBL) is a key component of innate immunity. MBL deficiency is common (10-30% of the general population depending on the definition used) and has been associated with disease progression in cystic fibrosis. We aimed to assess the effect of MBL deficiency on disease severity in non-cystic fibrosis bronchiectasis.
Mannose Binding Lectin Deficiency, Bacterial Infection and Disease Severity in Chronic Obstructive Pulmonary Disease: Towards Personalised Medicine for COPD
1/07/13 → 30/06/15
Chalmers, J. D., McHugh, B. J., Doherty, C., Smith, M. P., Govan, J. R., Kilpatrick, D. C., & Hill, A. T. (2013). Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study. The Lancet Respiratory Medicine, 1(3), 224-232. https://doi.org/10.1016/S2213-2600(13)70001-8