Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study

James D. Chalmers (Lead / Corresponding author), Brian J. McHugh, Catherine Doherty, Maeve P. Smith, John R. Govan, David C. Kilpatrick, Adam T. Hill

    Research output: Contribution to journalArticle

    48 Citations (Scopus)

    Abstract

    Mannose-binding lectin (MBL) is a key component of innate immunity. MBL deficiency is common (10-30% of the general population depending on the definition used) and has been associated with disease progression in cystic fibrosis. We aimed to assess the effect of MBL deficiency on disease severity in non-cystic fibrosis bronchiectasis.
    Original languageEnglish
    Pages (from-to)224-232
    Number of pages9
    JournalThe Lancet Respiratory Medicine
    Volume1
    Issue number3
    DOIs
    Publication statusPublished - May 2013

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