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Catheter-associated urinary tract infections (CAUTIs) are among the leading nosocomial infections in the world and have led to the extensive study of various strategies to prevent infection. However, despite an abundance of anti-infection materials having been studied over the last forty-five years, only a few types have come into clinical use, providing an insignificant reduction in CAUTIs. In recent decades, marine resources have emerged as an unexplored area of opportunity offering huge potential in discovering novel bioactive materials to combat human diseases. Some of these materials, such as antimicrobial compounds and biosurfactants synthesized by marine microorganisms, exhibit potent antimicrobial, antiadhesive and antibiofilm activity against a broad spectrum of uropathogens (including multidrug-resistant pathogens) that could be potentially used in urinary catheters to eradicate CAUTIs. This paper summarizes information on the most relevant materials that have been obtained from marine-derived microorganisms over the last decade and discusses their potential as new agents against CAUTIs, providing a prospective proposal for researchers.
|Number of pages||21|
|Publication status||Published - 29 Apr 2021|
- marine microorganisms
- urinary catheter
ASJC Scopus subject areas
- Drug Discovery
FingerprintDive into the research topics of 'Marine Microbial-Derived Antibiotics and Biosurfactants as Potential New Agents against Catheter-Associated Urinary Tract Infections'. Together they form a unique fingerprint.
- 1 Finished
Influence of Surface Properties of New Biomaterials for Catheters on Bacterial Adhesion Urine
Campbell, P., Corner, G., Davidson, F., Keatch, R., Nabi, G., Vorstius, J., Wilcox, K. & Zhao, Q.
Engineering and Physical Sciences Research Council
1/12/16 → 31/10/21