Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

Lijun Wang (Lead / Corresponding author), Yue Min, Doudou Xu, Fengjiao Yu, Wuzong Zhou, Alfred Cuschieri

    Research output: Contribution to journalArticlepeer-review

    16 Citations (Scopus)

    Abstract

    We report that FeO nanoparticles are able to catalyse lipid peroxidation in liposomes at acidic but not neutral pH. The oxidation is dependent on either pre-existing lipid peroxides or hydrogen peroxide as a substrate. This is the first evidence for metal oxide nanoparticles as peroxidase mimetics oxidising biomolecules in a relevant environment.
    Original languageEnglish
    Pages (from-to)11147-11150
    Number of pages4
    JournalChemical Communications
    Volume50
    Issue number76
    DOIs
    Publication statusPublished - 4 Oct 2014

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