Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

TY - JOUR

T1 - Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

AU - Wang, Lijun

AU - Min, Yue

AU - Xu, Doudou

AU - Yu, Fengjiao

AU - Zhou, Wuzong

AU - Cuschieri, Alfred

PY - 2014/10/4

Y1 - 2014/10/4

N2 - We report that FeO nanoparticles are able to catalyse lipid peroxidation in liposomes at acidic but not neutral pH. The oxidation is dependent on either pre-existing lipid peroxides or hydrogen peroxide as a substrate. This is the first evidence for metal oxide nanoparticles as peroxidase mimetics oxidising biomolecules in a relevant environment.

AB - We report that FeO nanoparticles are able to catalyse lipid peroxidation in liposomes at acidic but not neutral pH. The oxidation is dependent on either pre-existing lipid peroxides or hydrogen peroxide as a substrate. This is the first evidence for metal oxide nanoparticles as peroxidase mimetics oxidising biomolecules in a relevant environment.

UR - https://www.scopus.com/pages/publications/84906710735

U2 - 10.1039/c4cc03082f

DO - 10.1039/c4cc03082f

M3 - Article

AN - SCOPUS:84906710735

SN - 1359-7345

VL - 50

SP - 11147

EP - 11150

JO - Chemical Communications

JF - Chemical Communications

IS - 76

ER -