Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus

Andrea Ceci; Flavia Pinzari; Carmela Riccardi; Oriana Maggi; Lucia Pierro; Marco Petrangeli Papini; Geoffrey Michael Gadd; Anna Maria Persiani

doi:10.1007/s00253-017-8614-9

Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus

Andrea Ceci, Flavia Pinzari, Carmela Riccardi, Oriana Maggi, Lucia Pierro, Marco Petrangeli Papini, Geoffrey Michael Gadd, Anna Maria Persiani (Lead / Corresponding author)

Molecular Microbiology

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20 Citations (Scopus)

482 Downloads (Pure)

Abstract

The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.

Original language	English
Pages (from-to)	1019-1033
Number of pages	15
Journal	Applied Microbiology and Biotechnology
Volume	102
Issue number	2
Early online date	14 Nov 2017
DOIs	https://doi.org/10.1007/s00253-017-8614-9
Publication status	Published - 1 Jan 2018

Keywords

Biotransformation
Hexachlorocyclohexane
Medium pH
Metabolic phenotype
Soil saprotrophic fungi
Vanadium

ASJC Scopus subject areas

Biotechnology
Applied Microbiology and Biotechnology

Access to Document

10.1007/s00253-017-8614-9

Author Accepted Manuscript
The final publication is available at Springer via http://dx.doi.org/10.1007/s00253-017-8614-9
Accepted author manuscript, 916 KB

Tellurium and Selenium Cycling and Supply (Joint with Universities of Leicester, Durham, Edinburgh, Cardiff, Aberdeen and Open University and Natural History Museum)
Gadd , G. M. (Investigator)
1/05/15 → 4/03/20
Project: Research
COG3: The Geology, Geometallurgy and Geomicrobiology of Cobalt Resources Leading to New Product Streams (joint with Natural History Museum and Universities of Manchester, Bangor, Exeter, Loughborough and Southampton and Industrial Partner)
Gadd , G. M. (Investigator)
1/05/15 → 31/03/21
Project: Research

Cite this

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title = "Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus",

abstract = "The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.",

keywords = "Biotransformation, Hexachlorocyclohexane, Medium pH, Metabolic phenotype, Soil saprotrophic fungi, Vanadium",

author = "Andrea Ceci and Flavia Pinzari and Carmela Riccardi and Oriana Maggi and Lucia Pierro and {Petrangeli Papini}, Marco and Gadd, {Geoffrey Michael} and Persiani, {Anna Maria}",

note = "Financial assistance for this study and the related research project titled {"}Soil saprotrophic fungi in bioremediation of hexachlorocyclohexane-contaminated sites: metabolic, enzymatic and chemical aspects{"} (No. C26A14JSZ8) was provided by Sapienza University of Rome. Research support in the Geomicrobiology Group (GMG) is received from the Natural Environment Research Council (NE/M010910/1 (TeaSe); NE/M011275/1 (COG3)) which is gratefully acknowledged.",

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AU - Ceci, Andrea

AU - Pinzari, Flavia

AU - Riccardi, Carmela

AU - Maggi, Oriana

AU - Pierro, Lucia

AU - Petrangeli Papini, Marco

AU - Gadd, Geoffrey Michael

AU - Persiani, Anna Maria

N1 - Financial assistance for this study and the related research project titled "Soil saprotrophic fungi in bioremediation of hexachlorocyclohexane-contaminated sites: metabolic, enzymatic and chemical aspects" (No. C26A14JSZ8) was provided by Sapienza University of Rome. Research support in the Geomicrobiology Group (GMG) is received from the Natural Environment Research Council (NE/M010910/1 (TeaSe); NE/M011275/1 (COG3)) which is gratefully acknowledged.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.

AB - The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.

KW - Biotransformation

KW - Hexachlorocyclohexane

KW - Medium pH

KW - Metabolic phenotype

KW - Soil saprotrophic fungi

KW - Vanadium

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DO - 10.1007/s00253-017-8614-9

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JO - Applied Microbiology and Biotechnology

JF - Applied Microbiology and Biotechnology

IS - 2

ER -

Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus

Abstract

Keywords

ASJC Scopus subject areas

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Projects

Tellurium and Selenium Cycling and Supply (Joint with Universities of Leicester, Durham, Edinburgh, Cardiff, Aberdeen and Open University and Natural History Museum)

COG3: The Geology, Geometallurgy and Geomicrobiology of Cobalt Resources Leading to New Product Streams (joint with Natural History Museum and Universities of Manchester, Bangor, Exeter, Loughborough and Southampton and Industrial Partner)

Cite this