Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus

Andrea Ceci, Flavia Pinzari, Carmela Riccardi, Oriana Maggi, Lucia Pierro, Marco Petrangeli Papini, Geoffrey Michael Gadd, Anna Maria Persiani (Lead / Corresponding author)

Research output: Contribution to journalArticle

4 Citations (Scopus)
69 Downloads (Pure)

Abstract

The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.

Original languageEnglish
Pages (from-to)1019-1033
Number of pages15
JournalApplied Microbiology and Biotechnology
Volume102
Issue number2
Early online date14 Nov 2017
DOIs
Publication statusPublished - 1 Jan 2018

Fingerprint

Lindane
Poisons
Biotransformation
Fungi
Soil
Metals
Vanadium
Penicillium
Xenobiotics

Keywords

  • Biotransformation
  • Hexachlorocyclohexane
  • Medium pH
  • Metabolic phenotype
  • Soil saprotrophic fungi
  • Vanadium

Cite this

Ceci, A., Pinzari, F., Riccardi, C., Maggi, O., Pierro, L., Petrangeli Papini, M., ... Persiani, A. M. (2018). Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus. Applied Microbiology and Biotechnology, 102(2), 1019-1033. https://doi.org/10.1007/s00253-017-8614-9
Ceci, Andrea ; Pinzari, Flavia ; Riccardi, Carmela ; Maggi, Oriana ; Pierro, Lucia ; Petrangeli Papini, Marco ; Gadd, Geoffrey Michael ; Persiani, Anna Maria. / Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus. In: Applied Microbiology and Biotechnology. 2018 ; Vol. 102, No. 2. pp. 1019-1033.
@article{28e5b038cf1d4fbdbf795467b415f466,
title = "Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus",
abstract = "The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.",
keywords = "Biotransformation, Hexachlorocyclohexane, Medium pH, Metabolic phenotype, Soil saprotrophic fungi, Vanadium",
author = "Andrea Ceci and Flavia Pinzari and Carmela Riccardi and Oriana Maggi and Lucia Pierro and {Petrangeli Papini}, Marco and Gadd, {Geoffrey Michael} and Persiani, {Anna Maria}",
note = "Financial assistance for this study and the related research project titled {"}Soil saprotrophic fungi in bioremediation of hexachlorocyclohexane-contaminated sites: metabolic, enzymatic and chemical aspects{"} (No. C26A14JSZ8) was provided by Sapienza University of Rome. Research support in the Geomicrobiology Group (GMG) is received from the Natural Environment Research Council (NE/M010910/1 (TeaSe); NE/M011275/1 (COG3)) which is gratefully acknowledged.",
year = "2018",
month = "1",
day = "1",
doi = "10.1007/s00253-017-8614-9",
language = "English",
volume = "102",
pages = "1019--1033",
journal = "Applied Microbiology and Biotechnology",
issn = "0175-7598",
publisher = "Springer Verlag",
number = "2",

}

Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus. / Ceci, Andrea; Pinzari, Flavia; Riccardi, Carmela; Maggi, Oriana; Pierro, Lucia; Petrangeli Papini, Marco; Gadd, Geoffrey Michael; Persiani, Anna Maria (Lead / Corresponding author).

In: Applied Microbiology and Biotechnology, Vol. 102, No. 2, 01.01.2018, p. 1019-1033.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Metabolic synergies in the biotransformation of organic and metallic toxic compounds by a saprotrophic soil fungus

AU - Ceci, Andrea

AU - Pinzari, Flavia

AU - Riccardi, Carmela

AU - Maggi, Oriana

AU - Pierro, Lucia

AU - Petrangeli Papini, Marco

AU - Gadd, Geoffrey Michael

AU - Persiani, Anna Maria

N1 - Financial assistance for this study and the related research project titled "Soil saprotrophic fungi in bioremediation of hexachlorocyclohexane-contaminated sites: metabolic, enzymatic and chemical aspects" (No. C26A14JSZ8) was provided by Sapienza University of Rome. Research support in the Geomicrobiology Group (GMG) is received from the Natural Environment Research Council (NE/M010910/1 (TeaSe); NE/M011275/1 (COG3)) which is gratefully acknowledged.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.

AB - The saprotrophic fungus Penicillium griseofulvum was chosen as model organism to study responses to a mixture of hexachlorocyclohexane (HCH) isomers (α-HCH, β-HCH, γ-HCH, δ-HCH) and potentially toxic metals (vanadium, lead) in solid and liquid media. The P. griseofulvum FBL 500 strain was isolated from polluted soil containing high concentrations of HCH isomers and potentially toxic elements (Pb, V). Experiments were performed in order to analyse the tolerance/resistance of this fungus to xenobiotics and to shed further light on fungal potential in inorganic and organic biotransformations. The aim was to examine the ecological and bioremedial potential of this fungus verifying the presence of mechanisms that allow it to transform HCH isomers and metals under different extreme test conditions. To our knowledge, this work is the first to provide evidence on the biotransformation of HCH mixtures, in combination with toxic metals, by a saprotrophic non-white-rot fungus and on the metabolic synergies involved.

KW - Biotransformation

KW - Hexachlorocyclohexane

KW - Medium pH

KW - Metabolic phenotype

KW - Soil saprotrophic fungi

KW - Vanadium

U2 - 10.1007/s00253-017-8614-9

DO - 10.1007/s00253-017-8614-9

M3 - Article

VL - 102

SP - 1019

EP - 1033

JO - Applied Microbiology and Biotechnology

JF - Applied Microbiology and Biotechnology

SN - 0175-7598

IS - 2

ER -